Full: HTML / PDF (4319K) Select Citation Preparation, Stabilization, and Bioefficacy of β-Cyclodextrin Inclusion Compounds of Chloramidophos Shanshan Zhou, Lumei Wang, Anping Zhang, Kunde Lin, and Weiping Liu pp 2708 2713; (Article) DOI: 10.1021/jf703635p Abstract Full: HTML / PDF (240K) Select Citation http://pubs3.acs.org/acs/journals/toc.page?incoden=jafcau&indecade=0&involume=56&inissue=8 (...

Radioligand binding experiments were carried out to identify and characterize nonadrenoceptor [H]idazoxan binding sites and [H](1,2-di-(2-tolyl)guanidine) binding sites in the rat and human stomach. Furthermore, we examined two selected aspects of their potential functional significance. Binding of [H]idazoxan (Kd 5 11.1 nM and 12.4 nM, respectively) and [H]DTG (Kd 5 932 nM and 242 nM, respecti...

Purpose: Interleukin 13 receptor 2-chain (IL-13R 2) has been reported to be abundantly and specifically overexpressed in glioblastoma multiforme. Here we report the identification of a CTL epitope derived from the IL-13R 2. Experimental Design: Mature dendritic cells (DCs) were pulsed with each of the synthetic peptides that were designed, based on a binding affinity-based prediction and a prot...

Monoesters of 1,3-diols can be prepared with the mixed Tishchenko reaction from â-hydroxy aldehydes and another aldehyde. These two aldehydes form a diastereomeric mixture of 1,3-dioxan-4-ol hemiacetal derivatives which can be further converted to monoesters with suitable catalysts. Limitations in the formation and esterification of this hemiacetal intermediate have been investigated in this wo...

We show how the self-assembly of miktoarm star copolymers can be controlled by modifying the side chains of their polypeptide arms, using A2B and A2B2 type polymer/polypeptide hybrids (macromolecular chimeras). Initially synthesized PS2PBLL and PS2PBLL2 (PS, polystyrene; PBLL, poly(ε-tert-butyloxycarbonyl-L-lysine)) miktoarms were first deprotected to PS2PLLHCl and PS2PLLHCl2 miktoarms (PLLHCl,...

Due to a rapid increase in the number of vehicles, the need for parking spaces is on rise. It is important to park the cars in close proximity to avoid traffic congestion and use a parking area efficiently. Current car parking management systems utilize human personnel to find available parking areas or use a video based system that collects the information in the form of images and tracks avai...

We have determined the amino acid sequence of the variable (V) region of the 8 heavy (H) chain of human IgD isolated from the plasma ofmyeloma patient WAH. This V region is unusual in its amino end group (arginine) and in its length (129 residues). The length is due to 10 insertions in the third complementarity-determining region (CDR3). A computer search showed that no reported CDR3-joining re...

The Major Histocompatibility Complex (MHC) class II transactivator (CIITA) acts as a master switch to activate expression of the genes required for MHC-II antigenpresentation. During B-cell to plasma cell differentiation, MHC-II expression is actively silenced but the mechanism has been unknown. In plasma cell tumors such as multiple myeloma the repression of MHC-II is associated with the loss ...

The volatiles emitted by agar plate cultures of the xylarialean fungus Hypoxylon invadens were investigated by use of a closed loop stripping apparatus in combination with GC–MS. Several aromatic compounds were found that could only be identified by comparison to all possible constitutional isomers with different ring substitution patterns. For the set of identified compounds a plausible biosyn...

The Saccharomyces cerevisiae mismatch repair (MMR) protein MSH6 and the SGS1 helicase were recently shown to play similarly important roles in preventing recombination between divergent DNA sequences in a single-strand annealing (SSA) assay. In contrast, MMR factors such as Mlh1p, Pms1p, and Exo1p were shown to not be required, or to play only minimal roles. In this study we tested mutations th...