Accounting for less than 5% of all vulvar malignancies, primary carcinoma of the Bartholin gland is rare. Cancers arising in the Bartholin duct are most commonly adenocarcinomas or squamous cell carcinomas; occasionally transitional cell, adenosquamous, and adenoid cystic carcinomas may develop. A case of locally advanced Bartholin gland carcinoma was seen recently at Mayo Clinic. Case Report

Infiltrating syringomatous adenoma of the nipple is a rare, benign lesion with distinct clinical and histological features. Origin from ducts of dermal sweat glands has been postulated. Important differential diagnosis include nipple adenoma, tubular carcinoma and adenosquamous carcinoma. Appropriate local management includes accurate diagnosis and complete excision to avoid local recurrences. ...

Adenosquamous carcinoma is a rare form of colorectal cancer. It is believed to be more aggressive and carries a poorer prognosis compared to the more typical colonic adenocarcinomas. Here we describe a case of primary cecaladenosquamous carcinoma invading into the terminal ileum along with a review of the literature.

BACKGROUND Pancreatic adenosquamous carcinoma (PASC) is a rare subtype of pancreatic cancer characterized by a dual histological component and aggressive behavior. This form is not well known, its histogenesis is uncertain, and there are different opinions on the diagnostic histopathological criteria. The differential diagnosis with more common ductal adenocarcinoma, squamous cell carcinoma, sq...

BACKGROUND Studies have been reported that cyclin-dependent kinase5 (CDK5) was associated with the development of several cancers. However, the relationship between CDK5 level and clinicopathological factors is still poorly understood in cervical diseases. The aim of the current study was to investigate the expression of CDK5 and its clinical significance in variant cervical lesions. METHODS ...

Given the extended survival of patients diagnosed with cervical cancer, a large number of women are treated with radiotherapy. A second primary cancer has currently become one of the most important radiation-induced injuries as the number of cancer patients who are cured is increasing by virtue of recent advancements in therapeutic radiology. A 56-year-old woman developed two pelvic malignancie...

A 56-year-old female with history of stage IIA adenosquamous lung carcinoma treated 13 months prior to presentation with lobectomy, mediastinal lymph node dissection, and adjuvant chemotherapy, presented for several weeks of worsening dyspnea. Exam was non-focal aside from tachycardia. Computed tomography of the chest revealed a large 4 cm × 5 cm mass in the bilateral ventricular myocardium. Th...

Overall, colorectal cancer is the third most commonly diagnosed cancer in both men and women, meaning that it is one of the more widely recognized preventable cancers. Instances of colorectal malignancies though are overwhelmingly attributable to adenocarcinoma. Colorectal cancers with components of squamous cell carcinoma represent a statistical anomaly. Here, we present the case of a 50-year-...

Metaplastic carcinoma of the breast refers to a heterogenous group of mammary carcinomas that contain a mixture of various cell types, including squamous cells, spindle cells and/or a mesenchymal component, such as bone or cartilage. To the best of our knowledge, the clinical course of a tumour that has undergone a transformation from one type of metaplastic carcinoma to another subtype has not...

Introduction Lung lesions include a large variety of benign and malignant conditions. Lung carcinoma is the most common carcinoma in the world today, comprising 12.6% of all the cancers and 17.8% of all the [1] cancer deaths. Benign lesions include inflammatory conditions comprising of acute Inflammatory conditions, granulomatous inflammation, specific infections ( Aspergillus, Phycomycetes, Fu...