the lack of variation in antifungal drugs, and the misuse or inappropriate use usually causes resistant strains of the yeast in human’s normal flora. unfortunately, a large number of candida infection cases in immunosuppressed patients with insufficient treatment eventually can cause patient's death. the aim of this study was to evaluate the in vitro conventional antifungal azole compounds with...

background and objectives: vulvovaginal candidiasis is a common fungal infection among women during reproductive ages. although, candida albicans is accounted as the main etiologic agent of vaginitis, non- albicans species have arisen during last years. resistant to antifungal drugs especially, fluconazole has been more reported by researchers from around the world. the aims of this study were ...

conclusions garlic and zmb vaginal cream 2% can be used as an effective treatment option in cases of drug resistance and, also, by the people who are interested in treating with herbal medicines. results before treatment, all patients had positive candidiasis fungi culture, in both groups (100%). the positive culture was 14.1%, 15.2%, 10.3%, respectively, on day 7 after treatment and 2.6%, 0%, ...

background and objectives: vaginal candidiasis is a common disease in women during their lifetime and occurs in diabetes patients, during pregnancy and oral contraceptives users. although several antifungals are routinely used for treatment; however, vaginal candidiasis is a challenge for patients and gynecologists. the aim of the present study was to evaluate terbinafine (lamisil) on candida v...

Abstract Objective The objectives of this study were to investigate the antifungal susceptibility and genetic diversity Candida albicans isolated from HIV + patients with oropharyngeal candidiasis. A total 50 C. isolates cultured on Sabouraud glucose agar containing chloramophenicol. against fluconazole, clotrimazole, nystatin, amphotericin B, ketoconazole flucytosine was assessed using disc di...

The three imidazole antimycotics clotrimazole, miconazole, and ketoconazole all inhibit the demethylation of lanosterol to ergosterol, resulting in inhibition of growth of Saccharomyces cerevisiae; this is a fungistatic action. At higher concentrations clotrimazole and miconazole are fungicidal, whereas ketoconazole is not. The fungicidal action reflects direct membrane damage by the imidazoles...

The induction of different crystal morphologies is of crucial importance for many applications. In this work, the preparation of various crystal morphologies within clotrimazole films on glass substrates is demonstrated. Amorphous clotrimazole thin films were transformed via vapor annealing into crystalline structures; highly monodisperse/multidisperse crystallites, spherulite, or dendritic str...

Clotrimazole 1% (Canesten) cream was used in a trial comprising 138 men with candidal balanitis. Eighty-six (91%) out of 94 men were asymptomatic after seven days and 57 (98%) of 58 men were asymptomatic after three weeks' treatment. After seven days, Candida albicans could no longer be cultured from 86 (90%) of 96 men, nor from 55 (95%) of 58 men three weeks after treatment. Microscopical exam...