Endometrial cancer (EC) is a hormone-dependent cancer that currently represents the most frequent malignancy of the female reproductive tract. The involvement of steroid hormones in EC etiology and progression has been reported. More recently, gonadotropins, and, in particular LH/hCG, are emerging as novel regulators of tumor progression. In the present review, we discuss the role of the LH/hCG...

Introduction/Objective. Fetal growth restriction (FGR) is associated with increased fetal and neonatal mortality morbidity. The study objective was to investigate the correlation of maternal blood biochemical markers routinely determined in first second trimester screening ultrasound surveillance parameters prediction condition singleton pregnancies. Methods. In we measured serum levels beta su...

Human luteinizing hormone (hLH) and chorionic gonadotropin (hCG) act on the same receptor (LHCGR) but it is not known whether they elicit the same cellular and molecular response. This study compares for the first time the activation of cell-signalling pathways and gene expression in response to hLH and hCG. Using recombinant hLH and recombinant hCG we evaluated the kinetics of cAMP production ...

Objective. To test if serum hCG levels the morning after the ovulatory hCG injection correlate with (1) retrieval efficiency, (2) oocyte maturity, (3) embryo quality, (4) pregnancy, and/or (5) time to implantation in patients undergoing in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI). Design. Retrospective cohort analysis. Setting. University-based IVF clinic. Patient(...

Normal pregnancy is characterized by an early expansion of regulatory T cells (Tregs), which is known to contribute to fetal tolerance. However, mechanisms and factors behind Treg expansion are not yet defined. Recently, we proposed that the pregnancy hormone human chorionic gonadotropin (hCG) efficiently attracts human Tregs to trophoblasts, favoring their accumulation locally. In this study, ...

BACKGROUND The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) established a Working Group to investigate means of improving the comparability of immunoassays for human chorionic gonadotropin (hCG), which was selected as a prototype glycoprotein analyte. The Working Group identified development of unambiguous nomenclature and production of new highly purified Inter...

مطالعه حاضر به بررسی رمان خانه گرد اثر لوئیز اردریک در پرتو «مفهوم تأثیر» می‌پردازد. پاتریک کوم هوگان با ارائه نظریه تاثیر» روایت تجربه عاطفه و احساس سوژه ها را مورد هدف قرار می دهد. پژوهشگران این مقاله می‌‌کوشند تا مفاهیم عاطفه،روایت عاطفه، شرایط برانگیختن،همانند‌‌سازی،تعدیل ومنطقی‌سازی ردیابی‌کنند.سعی بر آن است فرایند پرداخته‌شود که چگونه روایت،احساسات عواطف همانند‌سازی می‌شوند پی تعدیل منطقی...

In type 1 diabetes mellitus, the impaired testosterone synthesis in testes leads to androgen deficiency. The long-term application of high gonadotropin doses for its correction decreases sensitivity luteinizing hormone/human chorionic (LH/hCG) receptors Leydig cells endogenous gonadotropins. aim this work was study effect a 3-day treatment male Wistar rats with streptozotocin 5-amino- N-tert -b...