Background: Determination of the impact of angiogenesis on tumor development and progression is essential. This study aimed to determine the serum levels of Vascular endothelial growth factor (VEGF) and Interleukin 6 (IL-6) in breast carcinoma, and to correlate them with tumor size, lymph node involvement, and cancer stage. Methods: Under aseptic precautions 5 ml of venous blood was collecte...

background: alpha-thalassemia syndrome includes a group of hereditary anemia in which expression of alpha globin chains is decreased or absent. impaired rbc in patients with thalassemia causes vessel involvement and endothelial cell vessel disturbance. vascular endothelial growth factor (vegf) is the most important regulator for endothelial cell proliferation. so, the aim of this study is to co...

   Background & Objective: The combination of two or more therapeutic agents and their synergetic impacts can be therapeutically effective against multifactorial diseases, such as diabetic foot ulcers. This study demonstrates the application of a nanofiber-based drug delivery system with a controlled release of the growth factor. Various studies have shown that vascular endothelial growth facto...

Objective(s): Previous study has indicated that triiodothyronine (T3) facilitated cartilage degeneration in osteoarthritis (OA). This study aimed to investigate the effects of T3 on angiogenesis-related factor expression in human osteoblasts of OA subchondral bone.Materials and Methods: The subchondral bone specimens were obtained from O...

vascular endothelial growth factor (vegf) is a multifunctional cytokine with distinct functions in angiogenesis, lymphangiogenesis, vascular permeability, and hematopoiesis. vegf is a highly conserved, disulfide-bonded dimeric glycoprotein of 34 to 45 kda produced by several cell types including fibroblasts, neutrophils, endothelial cells, and peripheral blood mononuclear cells, particularly t ...

the aim of this study was to examine the effect of swimming submaximal training and cadmium consumption on cardiac hif1-α and vascular endothelial growth factor (vegf) in pregnant rats. 32 pregnant wistar rats were randomly divided into 4 groups: cadmium, swimming, cadmium+swimming and control. experimental groups performed the swimming protocol for 3 weeks, 5 sessions a week for 60 minutes per...

background: vascular endothelial growth factor (vegf) is capable of initiating angiogenesis in blood vessels and may act as mitogenic agent for epithelium of odontogenic cysts and tumors. this study was conducted to evaluate the role of epithelial vegf expression in odontogenic cysts and ameloblastoma and its correlation with argyrophilic nucleolar organizer region counts to assess its role in ...