Acquiring induced pluripotent stem cells (IPSC) lines from probands with rare diseases allows investigating properties of difficult to obtain tissues. We obtained IPSC dermal fibroblasts two patients recessive form dystrophic epidermolysis bullosa (RDEB) using the kit Sendai virus mediated gene transfer. Patients have different mutation types in COL7A1 and RDEB forms. approved IPSCs status expr...

Genome sequencing of Fusarium oxysporum revealed that pathogenic forms of this fungus harbour supernumerary chromosomes with a wide variety of genes, many of which likely encode traits required for pathogenicity or niche specialization. Specific transcription factor gene families are expanded on these chromosomes including the EBR1 family (Enhanced Branching). The significance of the EBR1 famil...