An efficient serum marker for hepatocellular carcinoma (HCC) is currently lacking and requires intensive exploration. We aimed to evaluate the performance of des-gamma-carboxy prothrombin (DCP) for identifying hepatitis B virus-related HCC in a large, multicentre study in China. A total of 1034 subjects in three cohorts (A, B, and C) including HCC and various non-HCC controls were enrolled from...

OBJECTIVE This study aimed to identify the chemicals used by five printing workers and one coating worker who developed cholangiocarcinoma and estimate the workers' levels of chemical exposure. METHODS We obtained information on chemicals from the Ministry of Health, Labour and Welfare, Japan, and estimated working environment concentrations of the chemicals in printing and coating rooms and ...

An enzymeless sensor based on a multi-walled carbon nanotubes-dicetyl phosphate (MWCNT-DCP) film modified vitreous carbon electrode was developed for the determination of hypoxanthine. The MWCNT-DCP film modified electrode showed a remarkable enhancement effect on the oxidation peak current of hypoxanthine. Under the optimized conditions, the oxidation peak current is proportional to the concen...

Cytochrome P450-dependent oxidation and glutathione (GSH)-dependent conjugation are the primary routes of metabolism of haloalkanes. Using rat liver microsomes and cytosol, we investigated the metabolism of two halopropanes found on the U.S. Environmental Protection Agency Contaminant Candidate List, 1,3-dichloropropane (1,3-DCP) and 2,2-dichloropropane (2,2-DCP). An automated headspace techniq...

This paper describes and analyzes a novel MAC protocol named distributed-control polling (DCP), which has been designed to bring together the most interesting features of distributed-control MAC protocols (e.g., DQDB) and centralized token-passing MAC protocols (e.g. , FASNET, FDDI, EXPRESS-NET). From the fully distributed MAC protocols, DCP acquires the capability to guarantee both a complete ...

A Pseudomonas putida strain (MC4) that can utilize 2,3-dichloro-1-propanol (DCP) and several aliphatic haloacids and haloalcohols as sole carbon and energy source for growth was isolated from contaminated soil. Degradation of DCP was found to start with oxidation and concomitant dehalogenation catalyzed by a 72-kDa monomeric protein (DppA) that was isolated from cell lysate. The dppA gene was c...

Cognitive agents are able to perform categorical perception through physical interaction (active categorical perception; ACP), or passively at a distance (distal categorical perception; DCP). It is possible that the former scaffolds the learning of the latter. However, it is unclear whether DCP indeed scaffolds ACP in humans and animals, nor how a robot could be trained to likewise learn DCP fr...

The activation parameters for the ring-opening metathesis polymerization (ROMP) of endo(1) and exo-dicyclopentadiene (2), endo-1,2-dihydrodicylopentadiene (3), and norbornene (4) in the presence of Grubbs’ catalyst were determined using in situ NMR. The exo isomer of DCP was found to be more than an order of magnitude more reactive than the endo isomer. endo-DCP was found to have reactivity sim...

Traditionally, the signaled avoidance (SA) paradigm has been used in an attempt to better understand human phobia. Animal models of this type have been criticized for ineffectively representing phobia. The SA model characterizes phobia as an avoidance behavior by presenting environmental cues, which act as warning signals to an aversive stimulus (ie, shock). Discriminated conditioned punishment...

The hardness of the learning with errors (LWE) problem is one of the most fruitful resources of modern cryptography. In particular, it is one of the most prominent candidates for secure post-quantum cryptography. Understanding its quantum complexity is therefore an important goal. We show that under quantum polynomial time reductions, LWE is equivalent to a relaxed version of the dihedral coset...