background: dendritic cells (dcs) play a central role in the initiation and expansion of t cell mediated immune responses with potential immunotherapy application. the compounds which have the ability to induce immunomodulatory effects on dcs may be employed for the treatment of immunopathologic conditions such as autoimmune diseases. objective: the aim of this study was to investigate the in v...

objective(s)  garlic (allium sativum) is known as a potent spice and a medicine with broad therapeutic properties ranging from antibacterial to anticancer, and anticoagulant. one of the major purified garlic protein components is the 47 kda protein. in this study, the effect of 47 kda protein extracted from aged garlic (age) was evaluated on mouse dendritic cell (dc) maturation in vitro. materi...

the central role of dendritic cells (dcs) as bridging innate and adaptive immunity leads to the expanding use of these cells in the poultry vaccine studies. the most effective way to produce enough dcs is monocyte transformation by combined induction of interleukin-4 (il-4) and granulocyte-macrophage colony-stimulating factor (gm-csf). in this study full length of chicken il-4 (cil-4) cdna was ...