1. Comparisons were made in vitro at 25 degrees C among soleus and extensor digitorum longus (EDL) muscles from young (2-3 months), adult (9-10 months), and aged (26-27 months) male mice. We tested the hypotheses that, compared with soleus and EDL muscles of young and adult mice, those from aged mice develop decreased maximum tetanic force (P0, mN) and specific P0 (N/cm2), and that no significa...

Schwann cells polarize their surface membranes into several biochemically and ultrastructurally discrete regions of the myelin internode. To form these membrane domains, Schwann cells must sort, transport, and target membrane proteins appropriately. In this study, microtubule disassembly, confocal microscopy, and electron microscopic immunocytochemistry were used to investigate mechanisms invol...

In this paper we will investigate the growth of solutions of the linear differential equation f (n) + Pn−1(z)e f (n−1) + · · · + P0(z)ef = 0 where P0, . . . , Pn−1 are polynomials.

Consider a dynamic set of points in the plane having different colors. Let K1 and K2 be two keys according to which points may be sorted, e.g. the xand the y-coordinate. A point p ∈ S is called proper with respect to a query point p0 ∈ S iff K1(p0) < K1(p), K2(p0) < K2(p), and if p has a different color than p0. We present the colored quadrant priority search tree (CQPST) which supports the eff...

This paper criticizes the model and the new definition for osmotic pressure given by Parsafar et al. [J. Sci. I. R. Iran, Vol. 10, No. 4, 233 (1999)]. The model is a closed system containing 1 kg of solvent plus m mole of solute at constant temperature and under pressure P0 + ? where P0 is the standard pressure and ? is the osmotic pressure of the corresponding m molal solution. While the total...

Francisella tularensis subspecies tularensis, the etiological agent of tularemia, is highly pathogenic to humans and animals. However, the SCHU strain of F. tularensis SCHU P0 maintained by passaging in artificial media has been found to be attenuated. To better understand the molecular mechanisms behind the pathogenicity of F. tularensis SCHU, we attempted to isolate virulent bacteria by seria...

Sodium currents were recorded from motoneurons that were isolated from mice at postnatal days 0-8 (P0-P8) and maintained in culture for 12-24 hr. Motoneurons from normal mice exhibited a more than threefold increase in peak sodium current density from P0 to P8. For mice lacking a functional Scn8a sodium channel gene, motoneuronal sodium current density was comparable at P0 to that of normal mic...

The value of beta 2-microglobulin and neopterin concentrations in serum for early diagnosis of infants born to human immunodeficiency virus type 1 (HIV-1)-infected mothers was assessed. Concentrations of both markers were measured in serum samples from pediatric patients (Centers for Disease Control classifications P0, P1, and P2), as well as in age-matched normal subjects. Both beta 2-microglo...

Plants employ small RNA-mediated posttranscriptional gene silencing as a virus defense mechanism. In response, plant viruses encode proteins that can suppress RNA silencing, but the mode of action of most such proteins is poorly understood. Here, we show that the silencing suppressor protein P0 of two Arabidopsis-infecting poleroviruses interacts by means of a conserved minimal F-box motif with...