Human I(Ks) channels activate slowly with the onset of cardiac action potentials to repolarize the myocardium. I(Ks) channels are composed of KCNQ1 (Q1) pore-forming subunits that carry S4 voltage-sensor segments and KCNE1 (E1) accessory subunits. Together, Q1 and E1 subunits recapitulate the conductive and kinetic properties of I(Ks). How E1 modulates Q1 has been unclear. Investigators have va...

Proof. One direction is easy, namely TQBF ∈ PSpace. Once again, to achieve a spaceefficient algorithm, we use recursion. If the leading quantifier is ∃x, then we recursively check the two cases of setting x to 0 and 1, and return true if one of them is true. Similarly, if the leading quantifier is ∀x, then we recursively check the two cases of setting x to 0 and 1, and return true if both of th...

Two Australian isolates of Treponema hyodysenteriae which did not fit within the current serological grouping system for these bacteria were examined by agarose gel double immunodiffusion tests (AGDP). Isolate Vic1 was serologically unique, and we propose that it becomes the type organism for a new sixth serological group of T. hyodysenteriae (Group F). Isolate Q1 was unusual in that lipopolysa...

An e cient algorithm is presented that generates a hermite interpolation quaternion curve. Given two unit quaternions q1; q2 2 SO(3), and two tangent vectors v1 and v2 at q1 and q2, respectively; two great circular arcs C1(t) and C2(t), 0 t 1, are constructed so that C1(0) = q1, C 0 1(0) = v1, C2(1) = q1, and C 0 2(1) = v2. The two great circular arcs C1 and C2 are then smoothly blended togethe...

بخش‌بندی تأمین‌کنندگان، پایه و اساس تصمیمات مدیران زنجیره تأمین با هدف مدیریت توسعه تأمین‌کنندگان است. پژوهش حاضر ارائه رویکردی پویا برای طراحی استراتژی در این به‌دلیل اینکه علاوه بر ویژگی‌های اقلام خرید استراتژی‌ها نقش مهمی دارد، از دومرحله‌ای استفاده شده مرحله نخست، معیارهای مناسب رویکرد پرتفولیو طبقه‌بندی می‌شوند؛ سپس دوم، هر طبقه دو بُعد توانمندی تمایل متناسب بعُد می‌شوند. درنهایت بخش استراتژ...

BACKGROUND Innervation is a critical component of arrhythmogenesis and may present an important trigger/substrate modifier not used in current ventricular tachycardia (VT) ablation strategies. METHODS AND RESULTS Fifteen patients referred for ischemic VT ablation underwent preprocedural cardiac (123)I- meta-iodobenzylguanidine ((123)I-mIBG) imaging, which was used to create 3-dimensional (3D)...

In this paper, a gênerai technique is developed to enlarge the velocity space V^ of the unstable Qi/Qi-element by adding spaces V£ such that for the extended pair the Babuska-Brezzi condition is satisfied. Examples of stable éléments which can be derived in such a way imply the stability of the well-known Q2/Q1-element and the AQ1/Q1 -element. However, our new éléments are much more cheaper. In...

The reaction of [Et3NHI[@-CO)Cu-RS)Fe2(C0)6] with bis(1-alkyny1)mercw-y compounds gave different products depending on the nature of the organomercurial. Bis(phenylethyny1)mercury and bis( 1-hexyny1)mercury gave p-q1:q2-acetylide complexes, @-q1:q2-CsCR1)@-RS)Fe2(CO)6, while bis(3-methoxy-1-propyny1)mercury and bis(3-(dimethylamino)-l-propynyl)mercury formed doubly bridging vinylcarbyne product...

BACKGROUND Left ventricular (LV) dysfunction after orthotopic heart transplantation (OHT) is multifactorial and can be an indicator of graft rejection or coronary artery vasculopathy. Analysis of rotational mechanics may help in the early diagnosis of ventricular dysfunction. Studies describing the left ventricular rotational strain in children after OHT are lacking. It is important to establis...