The magnetic properties of thin-film multilayers [Fe/Py]/FeMn/Py are investigated as a function temperature and thickness the antiferromagnetic FeMn spacer using SQUID magnetometry. observed behavior differs substantially for structures with 6 nm 15 spacers. While structure exhibits exchange pinning both ferromagnetic layers in entire measurement interval from 5 to 300 K, becomes de-pinned vici...

Four new hybrid lead(II) halide perovskites, γ-(FA)2PbBr4, (FA)1.5(AA)0.5PbBr4, (PY)(GA)PbBr4 and (PY)(TZ)PbBr4 ((FA)=formamidinium, (AA)=acetamidinium, (PY)=pyrazolium, (GA)=guanidinium (TZ)=1,2,3-triazolium), adopt (110)-oriented layered perovskite structures. While (PY) is found to template the formation of ‘conventional’ structure types (i. e. containing staggered [PbBr4]∞ layers), (FA) sho...

OBJECTIVE To report the long-term safety data of certolizumab pegol (CZP) in rheumatoid arthritis (RA) accumulated as of 30 November 2011. DESIGN Data from 10 completed randomised controlled trials (RCT) of CZP in RA and several open-label extensions (OLE) were pooled across all doses. Reported adverse events (AE) occurred between the first dose and 84 days after the last dose. All deaths, se...

The phasing of neuronal activity in a rhythmic motor network is determined by a neuron's intrinsic firing properties and synaptic inputs; these could vary in their relative importance under different modulatory conditions. In the lobster pyloric network, the firing of eight follower pyloric (PY) neurons is shaped by their intrinsic rebound after pacemaker inhibition and by synaptic input from t...

Single crystals of [pyH(+)](2)[CuNb(2)(py)(4)O(2)F(10)](2)(-) and CuNb(py)(4)OF(5) were synthesized in a (HF)(x)().pyridine/pyridine/water solution (150 degrees C, 24 h, autogeneous pressure) using CuO and Nb(2)O(5) as reagents. The compound [pyH(+)](2)[CuNb(2)(py)(4)O(2)F(10)](2)(-) contains clusters of [CuNb(2)(py)(4)O(2)F(10)](2)(-) anions linked through N-H(+).F hydrogen bonds to the [pyH(+...

A glucose sensor was developed by electrocopolymerization using pyrroles containing a tris-bipyridine (bpy) osmium complex (Os-py), pyrrole (py), pyrrole propanoic acid (PPA) and glucose oxidase (GOx) to improve the key performance characteristics, such as the sensitivity, selectivity, and long-term stability. Tris-bipyridine osmium pyrrole complexes with four different methylene moieties were ...

University of Naples [6], Fraunhofer Institute for Experimental Software Engineering [7] and Centre for Software Maintenance [1,2]. These approaches all form their object structures based upon the dominance relations [8]. The dominance relations are obtained in the following way. In a call-directed-acyclic-graph (CDAG) a node px dominates a node py if and only if every path from the initial nod...

Polyomavirus (Py) DNA replication is regulated by its enhancer, which contains an AP1 site, c-Jun and c-Fos, the products of nuclear protooncogenes c-jun and c-fos, form the heterodimeric transcriptional activating factor AP1. Overexpression of c-fos and c-jun genes strongly stimulated Py DNA replication from the Py origin of replication as well as transcription from the Py early promoter throu...

BACKGROUND Statin therapy reduces the risk of occlusive vascular events, but uncertainty remains about potential effects on cancer. We sought to provide a detailed assessment of any effects on cancer of lowering LDL cholesterol (LDL-C) with a statin using individual patient records from 175,000 patients in 27 large-scale statin trials. METHODS AND FINDINGS Individual records of 134,537 partic...

Polyamides containing an N-terminal formamido (f) group bind to the minor groove of DNA as staggered, antiparallel dimers in a sequence-specific manner. The formamido group increases the affinity and binding site size, and it promotes the molecules to stack in a staggered fashion thereby pairing itself with either a pyrrole (Py) or an imidazole (Im). There has not been a systematic study on the...