117. Cannon CP, McCabe CH, Henry TD, Rogers WJ, Schweiger M, Gibson RS, Anderson JL, WilliamsDO, Braunwald E, for theTIMI 5 Investigators. Hirudinreduces reocclusion compared to heparin following thrombolysis in acutemyocardial infarction: results of the TIMI-5 trial.J AmColl Cardiol. 1993;21:136a.

BACKGROUND The Thrombolysis in Myocardial Infarction (TIMI) risk score uses clinical data to predict the short-term risk of acute myocardial infarction, coronary revascularization or death from any cause. It was originally developed for use in patients with unstable angina or non-ST-elevation myocardial infarction. We sought to expand the clinical application of the TIMI risk score by assessing...

Objectives: The goal of this study was to evaluate the long-term safety and efficacy of intracoronary epinephrine in reversing refractory no-reflow during primary percutaneous coronary intervention (PCI). Methods: A total of 248 consecutive patients with acute myocardial infarction who had been treated from September 2009 to November 2010 at the Cardiology Department of Turkiye Yuksek Ihtisas H...

AIMS The presence of residual thrombus following fibrinolytic therapy for ST-segment elevation myocardial infarction (STEMI) may predispose to greater embolization and microvascular dysfunction. METHODS AND RESULTS We hypothesized that even in the presence of a patent epicardial artery, residual thrombus would be associated with worsened TIMI myocardial perfusion grades (TMPG), independent of...

BACKGROUND Early resolution of ST-segment elevation (ST-segment recovery) is associated with an improved outcome after infarction. Whether this relation is present in patients with Thrombolysis In Myocardial Infarction (TIMI) grade 2 or 3 flow (ie, patent) infarct-related arteries is not known. METHODS AND RESULTS To examine the associations between time to achieve stable 50% ST-segment recov...

BACKGROUND Angiographic successful reperfusion in acute myocardial infarction has been defined as TIMI 3 flow. However, TIMI 3 flow does not always result in effective myocardial reperfusion. Myocardial blush grade (MBG) is an angiographic measure of myocardial perfusion. We hypothesized that optimal angiographic reperfusion is defined by TIMI 3 flow and MBG 2 or 3. METHODS AND RESULTS In 924...

BACKGROUND The aim of this study is to evaluate heart rate recovery (HRR) and association between coronary flow rate and HRR in patients with metabolic syndrome (MS) who had morphologically normal coronary angiogram. METHODS Study population included 43 patients with MS and 37 control subjects without MS. All patients were selected from individuals who had recently undergone coronary angiogra...