Background: The extended-spectrum beta-lactamase (ESBL) Klebsiella pneumoniae is one of the leading causes health-associated infections (HAIs), whose antibiotic treatments have been severely reduced. Moreover, HAI bacteria may harbor pathogenic factors such as siderophores, enzymes, or capsules, which increase virulence these strains. Thus, new therapies, antimicrobial photodynamic inactivation...

The purpose of this project was to develop and validate a pharmacokinetic model and to quantify the rate and extent of distribution between plasma and skin of two beta-lactam antibiotics, amoxicillin (AMX) and cefuroxime (CFX), which are frequently administered systemically to treat skin and skin structure infections. Dosing regimens are usually based on plasma concentration, however, concentra...

In present work, a compressor configuration is taken from literature which will be studied for aspect ratio (ratio between length of blade to chord length) influence over performance. Performance in the sense is pressure ratio of compressor. The aspect ratio of the blade is an important parameter and has a strong influence on the performance of axial flow compressor. There are so many literatur...

The aeroelastic response of a bird-damaged fan stage at the inlet of a high-bypass ratio turbofan engine is examined using a combined CFD/CSD model. ANSYS CFX is used for the computational fluid dynamic (CFD) calculations combined with the ANSYS Multifield (MFX) solver that couples ANSYS CFX with ANSYS Mechanical APDL to perform aeroelastic response calculations. The damaged fan sector consists...

This article presents a complementary experimental and computational investigation of the effect of viscosity and flowrate on the dynamics of drop formation in the dripping mode. In contrast to previous studies, numerical simulations are performedwith two popular commercial computational fluid dynamics (CFD) packages, CFX and FLOW-3D, both of which employ the volume of fluid (VOF) method. Compa...

Abstract. Numerical investigations of fluid structure interaction between unsteady flow and vibrating liner in a combustion chamber are undertaken. The computational study consist of two approaches. Firstly, a partioned procedure consists of coupling the LES code AVBP for combustion modelling with the FEM code CaluliX for structural dynamic analysis. The CFD code CFX together with the FEM Ansys...

The role of partially fluorinated carbon (CFx) supported platinum nanoparticles as proton exchange membrane fuel cell (PEMFC) electrodes in a hydrogen is investigated. CFx employed catalyst support via impregnation for oxygen reduction reaction (ORR) at various loadings to determine the optimal loading ORR and compared widely used (non-fluorinated) Vulcan Carbon (XC-72R). In half-cell testing, ...