BACKGROUND To date, the available non-invasive remedies for primary aldosteronism are not satisfactory in clinical practice. The phosphoinositide 3-kinase (PI3Ks)/protein kinase B (PKB or AKT)/mammalian target of rapamycin (mTOR) signaling pathway is essential for tumorigenesis and metastasis in many types of human tumors, including renal cancer, adrenal carcinoma and pheochromocytoma. The poss...

The sense of telepresence is very important in teleoperation environments in which the operator is physically separated from the vehicle. It appears reasonable, and it has already been shown in the literature, that extending the visual feedback with force feedback is able to complement the visual information (when missing or limited) through the sense of touch and allows the operator to better ...

objective: the aim of the this study was to investigate the prevalence of toxb, paa, lpf and iha adhesion genes in enteropathogenic escherichia coli (epec) isolates lacking in two important adhesion factors, the eaea and bfpa genes. methods: we examined a total of 70 serologically confirmed epec (eaea-, bfpa-) isolates. dna from the isolates was extracted by the phenol-chloroform method. toxb,...

Günümüzde kullanılan insansız hava araçlarının (İHA) neredeyse tamamı, küresel seyrüsefer uydu sistemini (Global Navigation Setallite System, GNSS) kullanmaktadır. Bu sistem, aracına yüksek hassasiyetli konum, hız ve zaman bilgisi sağlamaktadır. Ancak GNSS kullanıldığında, yapıların arasında, engebeli arazilerin bazı bölgelerinde kapalı alanlarda veri akışında aksaklıklar meydana gelmektedir. s...

The hyaluronan (HA) receptor for endocytosis (HARE; Stabilin-2) binds and clears 14 different ligands, including HA and heparin, via clathrin-mediated endocytosis. HA binding to HARE stimulates ERK1/2 activation (Kyosseva, S. V., Harris, E. N., and Weigel, P. H. (2008) J. Biol. Chem. 283, 15047-15055). To assess a possible HA size dependence for signaling, we tested purified HA fractions of dif...

BACKGROUND Burkholderia pseudomallei is an environmental Gram-negative bacillus and the cause of melioidosis. B. thailandensis, some strains of which express a B. pseudomallei-like capsular polysaccharide (BTCV), is also commonly found in the environment in Southeast Asia but is considered non-pathogenic. The aim of the study was to determine the distribution of B. thailandensis and its capsula...

Aims—To compare three commercial screening tests—the PanBio leptospiral IgM enzyme linked immunosorbent assay (ELISA), the Biolisa leptospiral IgM ELISA, and the indirect haemagglutination assay (IHA)—with the microscopic agglutination test (MAT) and two “in house” ELISAs— urease and horseradish peroxidase (HRP)— for the detection of leptospiral antibodies in a local UK and Eire population. Met...

BACKGROUND Alexithymia has been a familiar conception of psychosomatic phenomenon. The aim of this study was to investigate whether there were subtypes of alexithymia associating with different traits of emotional expression and regulation among a group of healthy college students. METHODS 1788 healthy college students were administered with the Chinese version of the 20-item Toronto Alexithy...

BACKGROUND The serology of amebiasis is affected by low sensitivity and specificity. OBJECTIVES To evaluate the advantage of the indirect hemagglutination assay and enzyme-linked immunosorbent assay in the diagnosis of amebiasis, using Entamoeba histolytica soluble antigen (macerated amebic antigens) prepared from four different virulent isolates, continuously cultivated in the presence of th...