Functional mature cells are continually replenished by stem cells to maintain tissue homoeostasis. In the adultDrosophilaposteriormidgut, both terminally differentiated enterocyte (EC) and enteroendocrine (EE) cells are generated from an intestinal stem cell (ISC). However, it is not clear how the two differentiated cells are generated from the ISC. In this study, we found that only ECs are gen...

We consider the design of nite element methods for the Naghdi shell model in the case when the deformation is bending dominated. Two formulations based on stabilizing techniques are introduced and it is proved that they are stable, hence free from locking. The theoretical estimates are connrmed by numerical benchmark studies. M ethodes d' el ements nis stabilis ees pour les coques a exion domin...

Epidermal electronic system (EES) is a class of integrated electronic systems that are ultrathin, soft, and lightweight, such that it could be mounted to the epidermis based on van der Waals interactions alone, yet provides robust, intimate contact to the skin. Recent advances on this technology will enable many medical applications such as to monitor brain or heart activities, to monitor prema...

Extraosseous Ewing's sarcoma (EES) is a rare soft tissue tumor that is histologically indistinguishable from the osseous form. We present the clinical course and magnetic resonance (MR) findings of a 30 year-old man with an EES in the right thigh. The soft tissue mass was well-defined with tissue characteristics of heterogenous intermediate signal intensity on T1and high signal intensity on T2-...

Early endosomes (EEs) are known to be a sorting station for internalized molecules destined for degradation, recycling, or other intracellular organelles. Segregation is an essential step in such sorting, but the molecular mechanism of this process remains to be elucidated. Here, we show that actin is required for efficient recycling and endosomal maturation by producing a motile force. Perturb...

We read with interest the article by Opperman and Benade, titled Analysis of the omega-3 fatty acid content of South African fish oil supplements: a follow-up study. 1 We make the following comments. In humans, long-chain omega-3 fatty acids are required in numerous cellular mechanisms and are converted in small amounts from the plant-based precursor alpha-linolenic acid. It therefore seemed pa...

Extraskeletal Ewing's sarcoma (EES) is a rare, soft tissue, malignant neoplasm histologically similar to skeletal Ewing's sarcoma. It occurs mainly in adolescents and young adults, and affects extremities in 36% of cases and central locations (commonly paravertebral regions) in the remainder. The differential diagnosis includes other small, blue, round cell tumours. A clinical case of EES invol...

The case of 20 years old boy with an extra osseous Ewing's sarcoma is described. He was initially diagnosed as a case of infiltrative malignant tumour of left suprarenal gland on the basis of preoperative workup but postoperative biopsy of surgically excised specimen confirmed Extra-osseous Ewing's Sarcoma (EES) suprarenal gland with no evidence of malignancy on skeletal scintiscan, bone marrow...