[This corrects the article on p. 451 in vol. 8, PMID: 25688182.].

objective(s): erythropoiesis is regulated by some extrinsic and intrinsic factors as micrornas (mirnas). mirnas are endogenously small non-coding regulatory rnas which play vital roles in the variety of cellular fate, critical processes; growth, apoptosis, metabolism, survival of the cells and specially differentiation. several mirnas such as mir-16 and mir-451 have been shown to be correlated ...

All-Pairs Shortest Paths: Earlier, we saw that Dijkstra’s algorithm and the Bellman-Ford algorithm both solved the problem of computing shortest paths in graphs from a single source vertex. Suppose that we want instead to compute shortest paths between all pairs of vertices. We could do this applying either Dijkstra or Bellman-Ford using every vertex as a source, but today we will consider an a...

MicroRNAs (miRNAs) play a pivotal role in the regulation of cellular gene expression via the conserved RNA interference (RNAi) mechanism. Biogenesis of the unusual miR-451 does not require Dicer. This molecule is instead processed by the Argonaute 2 (Ago2) enzyme. Similarly, unconventional short hairpin RNA (shRNA) molecules have been designed as miR-451 mimics that rely exclusively on Ago2 for...

The authors declare no competing financial interests. DNH and MRC designed research. DNH, CTP, and RK performed research. DNH, CTP, RGL, and MRC analyzed data. DNH, CTP, and MRC wrote the paper. Funding sources. This research was supported entirely by the Intramural Research Program of the NIH, National Institute on Aging. Correspondence should be addressed to: Dr. Mark R Cookson, Cell Biology ...

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New Strategies in Ewing’s Sarcoma: Lost in Translation? Running title: New Strategies in Ewing’s Sarcoma Fernanda I. Arnaldez, M.D., and Lee J. Helman, M.D. Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health Bethesda, MD Corresponding Author Fernanda I. Arnaldez, MD Assistant Clinical Investigator Center for Cancer Research NCI/NIH 10 Center Drive Room 1W-3816 B...