Advanced driver assistance systems (ADAS) have increasing demand for several sensor systems. Fusing multi-sensor data enlarges the field of view and increases the certainty and precision of the estimates. A crucial part of a fusion system is the data association, which requires data synchronization. The major synchronization strategies for data fusion are discussed and contrasted with respect t...

Road accidents cause a great loss to human lives and assets. Most of the accidents occur due to human errors, such as bad awareness, distraction, drowsiness, low training, and fatigue. Advanced driver assistance system (ADAS) can reduce the human errors by keeping an eye on the driving environment and warning a driver to the upcoming danger. However, these systems come only with modern luxury c...

In the coming decades, the number of older drivers that experiences difficulties in traffic as a result of functional limitations will strongly increase. Advanced Driver Assistance Systems (ADAS) could resolve some of these difficulties, by providing personal assistance in a road environment that does not always allow for the possibilities and limitations of the older road user. As a result, AD...

BACKGROUND TTP488, an antagonist at the Receptor for Advanced Glycation End products, was evaluated as a potential treatment for patients with mild-to-moderate Alzheimer's disease (AD). A previous report describes decreased decline in ADAS-cog (delta = 3.1, p = 0.008 at 18 months, ANCOVA with multiple imputation), relative to placebo, following a 5 mg/day dose of TTP488. Acute, reversible cogni...

The pharmacokinetics (PK) of biologic therapeutics, especially monoclonal antibodies (mAbs), in monkeys generally presents the most relevant predictive PK information for humans. However, human mAbs, xenogeneic proteins to monkeys, are likely to be immunogenic. Monkeys previously treated with a human mAb (nonnaïve) may have developed antidrug antibodies (ADAs) that crossreact with another test ...

In road-transportation terminology, ADAS (Advanced Driver Assistance System) is a combination of monitoring-, alarm-, and control systems for increasing safety level in vehicles. Most of ADAS systems are infrastructureindependent and autonomous. This means these systems must work without any external awareness systems on the roads during the drive. Nevertheless, there are some systems which can...

The control of immune-mediated transplant rejection by immunosuppressive agents might affect other human cells’ proliferation and function. This study aims to evaluate the effect of three immunosuppressants on the proliferation of human adipose-derived adult stroma (ADAS) and human umbilical vein endothelial cells (HUVEC). These cells were used as a culture model to study the minimum inhibitory...