Acute myeloid leukemia (AML) is a heterogeneous disorder of the hematopoietic system with no common genetic "Achilles heel" that can be targeted. Most patients respond well to standard therapy, while a majority relapse, and development of an effective therapy for AML patients is still urgently needed. In this study, we demonstrated that betulinic acid (BA) significantly increased Aryl hydrocarb...

Clean Development Mechanism (CDM) forestry project development requires highly multi-disciplinary and multiple-source information that can be complex, cumbersome and costly to acquire. Yet developing countries in which CDM projects are created and implemented are often data poor environments and unable to meet such complex information requirements. Using Cameroon as an example, the present pape...

This paper proposes a metering cost minimisation model that minimises sampling cost under the constraints of the required sampling accuracy of clean development mechanism (CDM) energy efficiency (EE) lighting project. Usually small scale (SSC) CDM EE lighting projects expect a crediting period of 10 years given that the lighting population will decay as time goes by. The SSC CDM sampling guidel...

Within the Kyoto Protocol, the clean development mechanism (CDM) is an instrument intended to reduce greenhouse gas emissions, while assisting developing countries in achieving sustainable development, with the multiple goals of poverty reduction, environmental benefits and cost-effective emission reductions. The CDM allows for a small percentage of emission reduction credits to come from affor...

PURPOSE This study aims to assess the fit of a number of exploratory and confirmatory factor analysis models to the 2010 Medical Council of Canada Qualifying Examination Part I (MCCQE1) clinical decision-making (CDM) cases. The outcomes of this study have important implications for a range of domains, including scoring and test development. METHODS The examinees included all first-time Canadi...

Most carbon abatement projects under the Kyoto Protocol’s Clean Development Mechanism (CDM) have been implemented in rapidly industrializing countries, notably China and India. To support small carbon abatement projects and to promote decarbonization in the least developed countries, the Programme of Activities (PoA) modality was introduced. But are the determinants of project implementation di...

This paper presents a systematic treatment of the linear theory of scalar gravitational perturbations in the synchronous gauge and the conformal Newtonian (or longitudinal) gauge. It differs from others in the literature in that we give, in both gauges, a complete discussion of all particle species that are relevant to any flat cold dark matter (CDM), hot dark matter (HDM), or CDM+HDM models (i...