A simple, rapid, and sensitive method for the simultaneous determination of vancomycin and cephalexin in human plasma was developed by using HPLC-DAD with second-order calibration algorithms. Instead of a completely chromatographic separation, mathematical separation was performed by using two trilinear decomposition algorithms, that is, PARAFAC-alternative least squares (PARAFAC-ALSs) and self...

Dedication For mom and dad.

Our family lived in basically a rural area outside Dalian. My Dad was really serious about education. When I was in primary school—well in the city, [schools] all have English classes, right? But in the country that's not the case. So my Dad took me every single night to the English teacher's house to study, then he'd come back later to pick me up.... By the time I started junior high, I'd alre...

This article presents a new method, which reduces costs and processing time for spatial object motion detection by focusing on the bare-hand motion that mimics computer mouse functions to allow the user to move the mouse pointer in real-time by the motion of his/her hand without any gloves worn, any object carried, or any key hit. In this article, the study of this topic is from the viewpoint o...

Este artigo descreve a caracterização por CLAE-DAD-EM/EM e CLAE-DEC dos perfis de metabólitos secundários de extratos das folhas de Lychnophora ericoides Mart. de diferentes procedências e suas propriedades citotóxicas e antioxidantes. Extratos foliares de populações representando sete diferentes localidades foram avaliados quanto à atividade antioxidante pelo sistema DPPH e à atividade citotóx...

Prolonged use of antiretroviral agents has been shown to reduce morbidity and mortality associated with human immunodeficiency virus (HIV) infection. However, the long term use of antiretroviral agents can result in adverse metabolic effects, including hyperlipidemia, insulin resistance, and diabetes. All of these metabolic consequences are risk factors for coronary artery disease and myocardia...

In the present study, a rapid fingerprint analysis of Ligusticum chuanxiong (L. chuanxiong) was developed based on ultra-fast liquid chromatography coupled with diode array detection (UFLC-DAD). The analysis time was shortened from approximately 75 min on conventional high-performance liquid chromatography (HPLC) to 40 min on UFLC. This method was validated in terms of stability [<4.40% relativ...

FeiYangchangweiyan capsule (FY capsule), a traditional Chinese medicinal preparation consisting of three medicinal herbs, has been used to treat bacterial dysentery, acute, and chronic gastroenteritis for several decades. In this study, a novel, convenient, accurate, and valid method was developed by using high-performance liquid chromatography (HPLC) coupled with diode array detection...

Crocins in commercial liquid saffron extracts (Saffr’activ®) were identified using high-performance chromatography (HPLC) with a diode array detector (DAD) and mass spectrometry (MS). The impact of storage on the qualities extract studied HPLC-DAD-MS by exposing trans-4-GG crocin to environmental factors. Light temperature induced degradation after only one week. Trans-4-GG was totally hydrolyz...

Address reprint requests to Dr. Jens D. Lundgren, DAD Coordinating Center, Copenhagen HIV Program, Section 044, Hvidovre University Hospital, 2650 Copenhagen, Denmark, or at [email protected] (Dr. Lundgren). *The members of the DAD study group are listed in the Appendix. N Engl J Med 2003;349:1993-2003. Copyright © 2003 Massachusetts Medical Society. background It remains controversial whether expos...