Identifying key cellular events that facilitate stem cell function and tissue organization is crucial for understanding the process of regeneration. Planarians are powerful model system to study regeneration and stem cell (neoblast) function. Here, using planaria, we show that the initial events of regeneration, such as epithelialization and epidermal organization are critically regulated by a ...

The A20/AN1 zinc-finger proteins (ZFPs) play pivotal roles in animal immune responses and plant stress responses. From previous gibberellin (GA) microarray data and A20/AN1 ZFP family member association, we chose Oryza sativa dwarf rice with overexpression of gibberellin-induced gene (OsDOG) to examine its function in the GA pathway. OsDOG was induced by gibberellic acid (GA(3)) and repressed b...

During animal development the establishment of a functional nervous system is an absolutely crucial step. Neurons send axons, sometimes over long distances to reach a certain target with very high accuracy. If errors occur during this process a wide range of neuronal defects can appear ranging from simple motor dysfunction to severe psychological diseases in humans. While increasing anatomical ...

Human immunodeficiency virus type 1 (HIV-1) causes a persistent viral infection resulting in the demise of immune regulatory cells. Clearance HIV-1 results integration proviral DNA into genome host cells, which provides means for evasion and long-term persistence. A therapeutic compound that specifically targets sustainably activates latent provirus could be transformative is goal “shock-and-ki...

Applied Physics Laboratory, University of Washington, Seattle, WA 98195 Department of Statistics, University of Washington, Seattle, WA 98195 Department of Neurological Surgery, University of Washington, Seattle, WA 98195 Department of Neurosurgery, University of Cambridge, Box 167, Addenbrooke’s Hospital, Cambridge, CB20QQ, United Kingdom Department of Bioengineering, University of Washington,...

سابقه و هدف: ورود گونه­­ های ماهی مهاجم دراکوسیستم ­های آبی، سبب بروز انواع اثرات منفی اکولوژیکی اقتصادی-اجتماعی می ­­شود. اولین گام در تجزیه تحلیل مخاطرات ناشی از گونه­ غیر­بومی، شناسایی خطر است بر این اساس ابزارهای متعددی برای ارزیابی خطرات تهاجمی غیربومی به منظور پشتیبانی تصمیم گیرندگان گونه ­­ها ایجاد شده است. هدف پژوهش قدرت تیلاپیای شکم قرمز (Coptodon zillii) حوضه آبریز تالاب شادگان (حوضه‌...

Abstract. Lossy compression has been applied to the data of large-scale Earth system model (ESMD) due its advantages a high ratio. However, few lossy methods consider both global and local multidimensional coupling correlations, which could lead information loss in approximation compression. Here, an adaptive method, hierarchical geospatial field representation (Adaptive-HGFDR), is developed ba...

در آشکار‌ساز CMS نسبت‌های انشعاب بوزون هیگز مدل استاندارد به جفت‌‌های J/ψ(1S) و cc ترتیب برابر 2-10×1/8 2-10×2/89 اندازه‌گیری شده است. لحاظ نظری یکی از سناریوهای ممکن برای تولید مستقیم این است که آغاز جفت واپاشی نماید سپس مرحله‌ی بعد هر یک کوارک‌های c طور مزون ترکش کنند. بر اساس سناریو مقاله بطریق کوارک‎های با استفاده نظریه اختلال مکانیک کوانتومی رنگ (pQCD) نظر گرفتن حالت‌های قطبش طولی عرضی محا...