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BACKGROUND Numerous explanatory randomized trials support the efficacy of chronic disease interventions, including smoking cessation treatments. However, there is often inadequate adoption of these interventions for various reasons, one being the limitation of generalizability of the explanatory studies in real-world settings. Randomized controlled trials can be rated as more explanatory versus...

Climate change may significantly affect the hydrological cycle and water resource management, especially in arid and semi-arid regions. In this paper, output from the Providing Regional Climates for Impacts Studies (PRECIS) regional climate model were used in conjunction with the Soil and Water Assessment Tool (SWAT) to analyse the effects of climate change on streamflow of the Xiying and Zamu ...

Clinical trials are sometimes classified as being explanatory or pragmatic, although they are rarely reported in that way. Explanatory trials may seek to investigate the efficacy of new treatments by imposing strict limitations on many aspects of trial design, including, for example, recruiting only those patients who are most likely to respond. In contrast, the objective of pragmatic trials is...

The regional climate models are being used to investigate the future projections of climate change and their impacts in developing and developed countries of the world in the recent era. The present study is carried out to study the downscaling ability of a regional climate model named PRECIS (Providing Regional Climates for Impacts Studies) of Hadley Centre, Meteorological Office, U. K in moun...

In this paper, the climate change scenarios of A2 and B2 for 2070-2100 time scale (denoted as 2080) several key locations India its impact on rice wheat crops based regional model (PRECIS) were described. The PRECIS projects an increase in temperature over most parts especially IGP (Indo-Gangetic Plains), region that presently experiences relatively low temperatures. Extreme high episodes rainf...