A novel metal–organic framework (MOF), with the formula [Cu(II)L]n (L=4, 4′-diamino diphenyl sulfone), has been synthesized conventionally andhydrothermally methods and characterized by FT-IR, PXRD, EDX, and SEMtechniques. The results MOFs were applied for photodegradation of MethyleneBlue (MB). The influence of affecting variables, such as initial MB dyeconcentrat...

GLUT1, the most ubiquitously expressed member of the GLUT family of glucose transporters, can be acutely activated by a variety of cell stresses. Methylene blue activates glucose transport activity of GLUT1 in L929 fibroblast cells presumably by a redox cycling of MB, which generates an oxidative stress. Data shown here reveal that methyl-beta-cyclodextrin (MCD) blocks both the staining of cell...

Myoglobin (Mb) catalyzes various two-electron oxidations; however, ferryl porphyrin cation radical equivalent to peroxidase compound I has not been identified yet. Distal histidine mutants of sperm whale Mb (His-64 --> Ala, Ser, and Leu) afford an apparent intermediate followed by the formation of a ferryl heme (Mb-II) in the reaction with m-chloroperbenzoic acid. Because the intermediate exhib...

Myoglobin (Mb) interaction with the outer mitochondrial membrane (OMM) promotes oxygen (O2) release. However, comprehensive molecular details on specific contact regions of OMM oxygenated (oxy-) and deoxygenated (deoxy-)Mb are missing. We used dynamics (MD) simulations to explore oxy- deoxy-Mb lipids in two lipid compositions: (a) a typical whole average, (b) specifically cardiolipin-enriched c...

ndrew G. C. Sutton, MA, MB, MRCP,* Philip G. Campbell, MB, MRCP,* ichard Graham, MB, MRCP,* Dallas J. A. Price, MB, MRCP,* Janine C. Gray, BSC(HONS), PHD,† ver D. Grech, MD, MRCP, FACC,* James A. Hall, MA, MD, FRCP,* lun A. Harcombe, MD, MRCP,* Robert A. Wright, MD, FRCP,* oger H. Smith, BSC(HONS), MB, FRCP,‡ Jerry J. Murphy, MB, BS, DM, FRCP,§ nanthaiah Shyam-Sundar, MB, BS, MD, DM, FRCP,‡ Mic...

The present study aimed to investigate the roles of the vascular endothelial cell growth factor (VEGF) and micro (mi)RNA-210 in the metastasis of primary medulloblastoma (MB) tumors. A total of 86 adult patients diagnosed with cerebellar MB were enrolled in the present study, of which 11 patients had metastatic MB in the subarachnoid space. The following samples were collected: MB primary tumor...

Incidence, Event Rates, and Early Outcome of Stroke in Dublin, Ireland: The North Dublin Population Stroke Study Peter J. Kelly, MD; Gloria Crispino, PhD; Orla Sheehan, MB; Lisa Kelly, MB; Michael Marnane, MB; Aine Merwick, MB; Niamh Hannon, MB; Danielle Ní Chróinín, MB; Elizabeth Callaly, MB; Dawn Harris, BSc; Gillian Horgan, BSc; Emma B. Williams, PhD; Joseph Duggan, MD; Lorraine Kyne, MD; Pa...