Reaction of 3,5-(CF(3))(2)PzLi with [Rh(μ-Cl)(η(2)-C(2)H(4))(2)](2) or [Rh(μ-Cl)(PMe(3))(2)](2) in Et(2)O gave the dinuclear complexes [Rh(η(2)-C(2)H(4))(2)(μ-3,5-(CF(3))(2)-Pz)](2) (1) and [Rh(2)(μ-Cl)(μ-3,5-(CF(3))(2)-Pz) (PMe(3))(4)] (2) respectively (3,5-(CF(3))(2)Pz = bis-trifluoromethyl pyrazolate). Reaction of PMe(3) with [Rh(COD)(μ-3,5-(CF(3))(2)-Pz)](2) in toluene gave [Rh(3,5-(CF(3))(...

Promazine derivatives induce cross-linking of bovine lens crystallins in vitro by irradiation with near-ultraviolet (UV) light in the presence of O2, as revealed by electrophoresis after denaturation. With the five derivatives tested (promazine [PZ], chlorpromazine [CPZ], triflupromazine [ TFPZ ], methoxypromazine [ MTPZ ], and acepromazine [ ACPZ ] ), single-hit kinetics are observed. Evidence...

Induced pluripotent stem (iPS) cells are a valuable resource for discovery of epigenetic changes critical to cell type-specific differentiation. Although iPS cells have been generated from other terminally differentiated cells, the reprogramming of normal adult human basal prostatic epithelial (E-PZ) cells to a pluripotent state has not been reported. Here, we attempted to reprogram E-PZ cells ...

PURPOSE To identify and evaluate textural quantitative imaging signatures (QISes) for tumors occurring within the central gland (CG) and peripheral zone (PZ) of the prostate, respectively, as seen on in vivo 3 Tesla (T) endorectal T2-weighted (T2w) MRI. MATERIALS AND METHODS This study used 22 preoperative prostate MRI data sets (16 PZ, 6 CG) acquired from men with confirmed prostate cancer (...

Plant stem cell populations, unlike their animal counterparts, do not use cell migration and oriented cell divisions to maintain their size, and therefore require a precise coordination between self-renewing divisions of stem cells, and rates of cell division and differentiation among stem cell progenitors. Shoot apical meristems (SAMs) of higher plants harbor a set of stem cells within the cen...

Protein Z-dependent protease inhibitor (ZPI) is a 72-kd member of the serpin superfamily of proteinase inhibitors that produces rapid inhibition of factor Xa in the presence of protein Z (PZ), procoagulant phospholipids, and Ca(++) (t(1/2) less than 10 seconds). The rate of factor Xa inhibition by ZPI is reduced more than 1000-fold in the absence of PZ. The factor Xa-ZPI complex is not stable t...

A poly (vinylchloride) (PVC) membrane electrode selective for prazosinium cation based on prazosinium-phosphotungstate (PZ)(3)PT ion-associate is prepared. The electrode exhibits a linear response with an approximate Nernstian slope over the range of 2.7 x 10(-6)-10(-2) M. Calibration graph slope of the electrode is 58 mV PZ(-1) concentration decade when preconditioned by soaking in distilled w...

A tape peeling model based on the geometry of the peel zone (PZ) is derived to predict the peeling behavior of adhesive tapes at peel angles less than or equal to 90o. The PZ model adds an angle-dependent multiplier to the ‘Kendall equation’ that takes into account the geometrical changes within the peel zone. The model is compared to experimental measurements of the peel force at different ang...

Protein Z-dependent protease inhibitor (ZPI) is a 72-kd member of the serpin superfamily of proteinase inhibitors that produces rapid inhibition of factor Xa in the presence of protein Z (PZ), procoagulant phospholipids, and Ca11 (t1/2 less than 10 seconds). The rate of factor Xa inhibition by ZPI is reduced more than 1000-fold in the absence of PZ. The factor Xa–ZPI complex is not stable to so...