Oral rehydration solution (ORS) was established as the cornerstone of therapy for dehydration secondary to acute infectious diarrhea approximately 40 years ago. The efficacy of ORS is based on the ability of glucose to stimulate Na and fluid absorption in the small intestine via a cyclic AMP-independent process. Despite the establishment that ORS is the primary reason for the substantial reduct...

The purpose of the present investigation was to prepare an intranasal in situ gel with increased nasal residence time in order to improve bioavailability of metoprolol tartrate. The in situ gel systems containing carbopol, hydroxypropyl methylcellulose K4M and K15M in different concentrations were prepared. The samples were characterized for viscosity, rheological behavior, gelation behavior, g...

To test the hypothesis that genetic instability correlates with malignant potential, we compared the rate of generation of marker chromosomal abnormalities in clones of B16 F1 and B16 F10 murine melanoma. These rates were estimated through an adaptation of fluctuation analysis of Luria and Delbruck (S. E. Luria and M. Delbruck, Genetics, 28: 491-511, 1943). The highly metastatic F10 line showed...

Background & objectives: Cell phone microwave (MW) is one of the most harmful physical agents in modern society. This study was designed to determine the effects of exposure to cell phone microwaves on mice sperm morphologic indices. Methods: Animals were divided into two groups including: Microwave (MW) (n=6; exposed to 950-MHz cell phone MW with 5 W output power density and 200 KHz modulatio...

Cancer stem cells (CSC) have raised great excitement during the last decade and are promising targets for an efficient treatment of tumors without relapses and metastases. Among the various methods that enable to enrich cancer cell lines in CSC, tumorspheres culture has been predominantly used. In this report, we attempted to generate tumorspheres from several murine and human cancer cell lines...

This chapter surveys work on dynamic heterogeneous agent models (HAMs) in economics and finance. Emphasis is given to simple models that, at least to some extent, are tractable by analytic methods in combination with computational tools. Most of these models are behavioral models with boundedly rational agents using different heuristics or rule of thumb strategies that may not be perfect, but p...

To evaluate the effect of orientation of hams during electromagnetic scanning on the estimation of dissected lean content, hams were scanned horizontally, posterior first (POS) or dorsal first (DOR), and vertically, medial side (aitchbone) first (MED; standing on the butt face). Weight and percentage of dissected lean were estimated using scan peak for each orientation, ham weight, and fat thic...

Laminin is an important promoter of cell-matrix interactions. A number of active laminin domains have been defined by use of synthetic peptides. The Tyr-Ile-Gly-Ser-Arg (YIGSR) sequence on the B1 chain in laminin can decrease tumor growth and metastasis, whereas another sequence containing Ser-Ile-Lys-Val-Ala-Val (SIKVAV) on the A chain can increase tumor growth and metastasis. Here, we selecte...

The aim of this study was to investigate the influence of MHS genotype on growth and development of muscle and fatty tissue in pig hams. The investigation was performed on 72 barrows divided into 4 groups according to genotype (NN and Nn) and feeding regime (standard and intensive). The data for analyses were collected by MRT imaging; the coefficients of allometric growth were calculated using ...