The solution structure of the C-terminal fragment 205-316 of thermolysin has been determined by 1H-NMR methods. The fragment forms a dimer in which each subunit has two different regions: the largely disordered N-terminal segment 205-260 and the structurally well-defined segment 261-316. The structured part of each subunit is composed of three helices and is largely coincident with the correspo...

a Institut für Organische Chemie der Technischen Universität Graz, Stremayrgasse 16, A-8010 Graz, Austria. Fax: +43 316 873 8740; Tel: +43 316 873 8751; E-mail: [email protected] b Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Fax: +1 626 568 8743; Tel: +1 626 395 4162; E-mail: [email protected] c Institut für Molek...

The Southeast Asian Universities Agroecosystem network (SUAN) has used five system properties to assess agroecosystem performance: productivity, stability, sustainability, equitability and autonomy. Assessing these properties can be useful for agricultural research and development, but the assessment is complicated by several factors. First is the multidimensional character of these properties,...

http://www.sciencemag.org/cgi/content/full/316/5831/1622 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/316/5831/1622/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http:/...

INTRODUCTION When diagnosing Pneumocystis jirovecii pneumonia (PJP), the clinical suspicion must be confirmed by laboratory tests. PJP is rarely described in patients with idiopathic CD4+ lymphocytopenia (ICL), a rare T-cell deficiency of unknown origin with persistently low levels of CD4+ T-cells (<300 µl-1 or <20 % of total lymphocytes) but repeated negative human immunodeficiency virus (HIV)...