We describe various computing techniques for tackling chessboard domination problems and apply these to the determination of domination and irredundance numbers for queens’ and kings’ graphs. In particular we show that γ(Q15) = γ(Q16) = 9, confirm that γ(Q17) = γ(Q18) = 9, show that γ(Q19) = 10, show that i(Q18) = 10, improve the bound for i(Q19) to 10 ≤ i(Q19) ≤ 11, show that ir(Qn) = γ(Qn) fo...

Ubiquitin chains of different topologies trigger distinct functional consequences, including protein degradation and reorganization of complexes. The assembly of most ubiquitin chains is promoted by E2s, yet how these enzymes achieve linkage specificity is poorly understood. We have discovered that the K11-specific Ube2S orients the donor ubiquitin through an essential noncovalent interaction t...

Parameter Estimate Reaction k1f 0.01 nM−1 s−1 S+L → SL k1b 0.059 s−1 SL → S+L k2 0.1 s−1 SL (+ATP) → SLP (+ADP) k3f 0.001 s−1 SLP → SP k3b 0.001 s−1 SP → SLP k4f 0.0238 nM−1 s−1 SLP+R → SLP·R k4b 0.001 s−1 SLP·R → SLP+R k5f 0.0238 nM−1 s−1 SP+R → SP·R k5b 0.001 s−1 SP·R → SP+R k6f 19.8 s−1 SLP·R → SL+RP k6b 0.001 nM−1 s−1 SL+RP → SLP·R k7f 19.8 s−1 SP·R → S+RP k7b 0.001 nM−1 s−1 S+RP → SP·R k8f...

Table 1. Numeric Values of Input Quantities of the Model for the Reference State The data are grouped into concentrations of pathway components, dissociation constants of protein complexes, concentration ratios, fl uxes and fl ux ratios, and characteristic times of selected processes. Experimental evidence for these data is discussed in the text. From these data, the following rates and rate co...

Dynamic oscillation of the Min system in Escherichia coli determines the placement of the division plane at the midcell. In addition to stimulating MinD ATPase activity, we report here that MinE can directly interact with the membrane and this interaction contributes to the proper MinDE localization and dynamics. The N-terminal domain of MinE is involved in direct contact between MinE and the m...

There is an increasing trend for Multi-National Enterprises (MNEs) to off-shore R&D activities to developing countries where Intellectual Property regimes (IP) are weak. Prior work in international trade theory suggests that there is limited technology transfer by MNE to destinations with weak IP regimes. However, there is considerable evidence that MNE offshore significant levels of R&D, over ...

This study aims to understand the relationship between capabilities of Escherichia coli strains to form biofilm and serotype groups expressed on cell surface. Sixteen strains of E. coli were originally isolated from different food processing lines in different Moroccan cities. Strains serotyped based on their O (somatic), H (flagellar), and K (capsular) surface antigen profiles using different ...

This paper examines the impact of women’s property inheritance rights on their educational attainment. Using exogenous variation created by femalefriendly state level reforms to the inheritance law in India, I find that educational attainment of women who were of primary school-going age at the time of reform increased by an average of 0.5 years in reforming relative to non-reforming states. Th...

This is a survey of the field of economic analysis of law, focusing on the work of economists. The survey covers the three central areas of civil law — liability for accidents (tort law), property law, and contracts — as well as the litigation process and public enforcement of law. Forthcoming in A.J. Auerbach and M. Feldstein, Handbook of Public Economics JEL Classes K00, K10, K11, K12, K13, K...