Cardiac magnetic resonance (CMR) diffusion tensor imaging (DTI) is a promising technique capable of probing the myocardial microstructure by assessing the myofiber orientation. New technical developments in CMR DTI in recent years have allowed the clinical application of this powerful imaging technique. CMR DTI has been used to study myocardial infarction and hypertrophic cardiomyopathy in pati...

Introduction: Diffusion tensor MRI (DTI) has become a powerful tool for the investigation into tissue architecture and integrity. However, there are numerous anatomical details in the brain that are undetectable at typical DTI image resolution, being 8mm3 voxels, due to partial volume effects and the sequence used in the majority of DTI studies, single -shot EPI, is sensitive to magnetic field ...

Schema-based data transformation and integration (DTI) has been an active research area for some time, while more recent advances in ontologies have led to significant research in ontology-based DTI. These two approaches present some overlaps and some differences, and in this paper we investigate possible synergies between them. In particular, we show how ontologies can enhance schema-based DTI...

Introduction: Higher B0 fields are expected to optimize fiber tracking and to increase the signal-to-noise ratio which should lead to higher spatial resolution of DTI [1,2]. However, at high fields B1 inhomogeneities are strong and result in sever distortions and signal voids in DTI. The B1 inhomogeneity results in ill-defined pulse angles that vary considerably over the probe volume. Parallel ...

PURPOSE The UNC-Utah NA-MIC DTI framework represents a coherent, open source, atlas fiber tract based DTI analysis framework that addresses the lack of a standardized fiber tract based DTI analysis workflow in the field. Most steps utilize graphical user interfaces (GUI) to simplify interaction and provide an extensive DTI analysis framework for non-technical researchers/investigators. DATA W...

Purpose Congruent with the world-wide call to combat global warming concerns within context of advancements in smart technology, artificial intelligence, robotics, algorithms (STARA), and digitalisation, organisational leaders are being pressured ensure that talented employees effectively managed (nurtured retained) curb potential risk staff turnover. By managing such talent(s), organisations m...

Relatively little is known about reliability of longitudinal diffusion-tensor imaging (DTI) measurements despite growing interest in using DTI to track change in white matter structure. The purpose of this study is to quantify within- and between session scan-rescan reliability of DTI-derived measures that are commonly used to describe the characteristics of neural white matter in the context o...

Normal-appearing white matter (NAWM) surrounding WMHs is associated with decreased structural integrity and perfusion, increased risk of WMH growth, and is referred to as the WMH penumbra. Studies comparing structural and cerebral blood flow (CBF) penumbras within the same individuals are lacking, however, and would facilitate our understanding of mechanisms resulting in WM damage. This study a...

Previous ex vivo diffusion tensor imaging (DTI) studies on formalin-fixed myocardial tissue assumed that, after some initial changes in the first 48 hr since the start of fixation, DTI parameters remain stable over time. Prolonged preservation of cardiac tissue in formalin prior to imaging has been seen many times in the DTI literature as it is considered orderly. Our objective is to define the...

BACKGROUND Diffusion tensor imaging (DTI) is a sensitive method for detecting white matter damage, and in cross sectional studies DTI measures correlate with age related cognitive decline. However, there are few data on whether DTI can detect age related changes over short time periods and whether such change correlates with cognitive function. METHODS In a community sample of 84 middle-aged ...