Previous studies suggest the lumbosacral (LS) spinal cord processes acute colorectal stimuli whereas the thoracolumbar (TL) and LS spinal segments process inflammatory stimuli. In this study, the effects of colorectal distention (CRD) on TL and LS dorsal horn neuronal activity were recorded in Nembutal-anesthetized male rats both with and without colonic inflammation. Both single cells (before ...

For 50 years since their discovery, the malaria parasite liver stages (LS) have been difficult to analyze, impeding their utilization as a critical target for antiinfection vaccines and drugs. We have undertaken a comprehensive transcriptome analysis in combination with a proteomic survey of LS. Green fluorescent protein-tagged Plasmodium yoelii (PyGFP) was used to efficiently isolate LS-infect...

BACKGROUND/AIMS Liver congestion due to heart failure in patients with valvular heart disease (VHD) can result in an overestimate of the liver stiffness (LS) as assessed by transient elastography (TE). This prospective pilot study investigated the dynamics of LS during the perioperative valve operation period. METHODS Thirty-two patients who underwent a valve operation (case) and 12 who under...

BACKGROUND Lynch syndrome (LS) is the most common hereditary colon cancer syndrome, accounting for 3-5% of colorectal cancer (CRC) cases, and it is associated with the development of other cancers. Early detection of individuals with LS is relevant, since they can take advantage of life-saving intensive care surveillance. The debate regarding the best screening policy, however, is far from bein...

It is not obvious how to extend Shannon’s original information entropy to higher dimensions, and many different approaches have been tried. We replace the English text symbol sequence originally used to illustrate the theory by a discrete, bandlimited signal. Using Shannon’s later theory of sampling we derive a new and symmetric version of the second order entropy in 1D. The new theory then nat...

BACKGROUND Factors associated with liver stiffness (LS) are unknown and normal reference values for LS have not been established. Individuals at high risk for alcoholic (ALD) and non-alcoholic fatty (NAFLD) liver disease need to be non-invasively discriminated during routine health checks. Factors related to LS measured using a FibroScan and normal reference values for LS are presented in this ...

BACKGROUND To identify factors which determine high life satisfaction (LS) and to analyse the prognostic influence of LS on mortality. METHODS Data collection was conducted on 2,675 participants, age 25-74 years, as part of the MONICA Augsburg Project 1994-95. Multivariate logistic regression analyses were used to determine factors associated with high LS (measured with one item, 6-level Like...

Lipedematous scalp (LS) and Lipedematous Alopecia (LA) are uncommon disorders of unknown etiology, pathogenesis and treatment. They are characterized by thickening of the subcutaneous layer of the scalp and a boggy scalp on palpation. Also, hair loss or shortening of hair is seen in LA. In this report, we describe LS in a 42-year-old woman presented with a diffuse thickened and spongy scalp. To...