The IETF developed the RPL routing protocol for Low power and Lossy Networks (LLNs). RPL allows for automated setup and maintenance of the routing tree for a meshed network using a common objective, such as energy preservation or most stable routes. To handle failing nodes and other communication disturbances, RPL includes a number of error correction functions for such situations. These error ...

Recurrent pregnancy loss (RPL) has many known aetiologies. However, using current diagnostic testing, a large fraction of recurrent pregnancy losses remain unexplained. Many of these may have immune underpinnings. HLA-G is a non-classical MHC class I product whose fairly restricted expression at the maternal-fetal interface suggests a role in successful embryonic implantation and/or subsequent ...

We have previously shown an extensive load of somatic copy number variations (CNVs) in the human placental genome with the highest fraction detected in normal term pregnancies. Hereby, we hypothesized that insufficient promotion of CNVs may impair placental development and lead to recurrent pregnancy loss (RPL). RPL affects ~3% of couples aiming at childbirth and idiopathic RPL represents ~50% ...

Recurrent Pregnancy Loss (RPL) is a disease, defined by two or more failed pregnancies, affecting about 5% pregnant women. RPL can be classified into primary RPL and secondary RPL [2]. Primary RPL aborters are those who have lost all previous pregnancies and have no live birth. Secondary RPL aborters are those who have at least one successful pregnancy, irrespective of the number of pregnancy l...

We report molecular genetic studies of three genes involved in early germ-line proliferation in Caenorhabditis elegans that lend unexpected insight into a germ-line/soma functional separation of autosomal/X-linked duplicated gene pairs. In a genetic screen for germ-line proliferation-defective mutants, we identified mutations in rpl-11.1 (L11 protein of the large ribosomal subunit), pab-1 [a po...

OBJECTIVE The goal of this study was to evaluate the etiologies and clinical outcomes of Korean recurrent pregnancy loss (RPL) patients. And also, we investigated the differences between primary and secondary RPL patients, between two and three or more pregnancy losses. METHODS One hundred seventy eight women diagnosed as RPL were enrolled. We performed chromosomal analysis, thyroid stimulati...