Much local government has been using large scale digital maps with Geographic Information System (GIS). However, the updating method of a map is not established yet. The purpose of this study is the real-time renewal of the digital map for local government by collaboration of REAR TIME GIS and spatial data. In this study, spatial data means Remote Sensing imageries and Real-time Kinematic Globa...

Animal development requires that positional information act on the genome to control cell fate and cell shape. The primary determinant of animal cell shape is the cytoskeleton and thus the mechanisms by which extracellular signals influence the cytoskeleton are crucial for morphogenesis. In the developing Drosophila compound eye, localized polymerization of actin functions to constrict the apic...

Signaling by DER, the Drosophila epidermal growth factor receptor tyrosine kinase (RTK), is essential for proper migration and survival of midline glial cells (MGCs) in the embryonic central nervous system (CNS) [1-4]. We recently isolated a gene called split ends (spen) in a screen designed to identify new components of the RTK/Ras pathway [5]. Drosophila Spen and its orthologs are characteriz...

Using mobile smart devices to provide urban location-based services (LBS) with sub-meter-level accuracy (around 0.5 m) is a major application field for future global navigation satellite system (GNSS) development. Real-time kinematic (RTK) positioning, which is a widely used GNSS-based positioning approach, can improve the accuracy from about 10-20 m (achieved by the standard positioning servic...

Receptor tyrosine kinases (RTK) are therapeutic targets for the treatment of malignancy. However, tumor cells develop resistance to targeted therapies through the activation of parallel signaling cascades. Recent evidence has shown that redundant or compensatory survival signals responsible for resistance are initiated by nontargeted glycoprotein RTKs coexpressed by the cell. We hypothesized th...

Receptor tyrosine kinase (RTK) targeted therapy has been explored for glioblastoma treatment. However, it is unclear which RTK inhibitors are the most effective and there are no predictive biomarkers available. We recently identified the RTK AXL as a putative target for the pan-RTK inhibitors cediranib and sunitinib, which are under clinical trials for glioblastoma patients. Here, we provide ev...

Global Navigation Satellite System Real-time Kinematic (GNSS-RTK) is an indispensable source for the absolute positioning of autonomous systems. Unfortunately, performance GNSS-RTK significantly degraded in urban canyons, due to notorious multipath and Non-Line-of-Sight (NLOS). On contrary, LiDAR/inertial odometry (LIO) can provide locally accurate pose estimation structured scenarios but subje...

Ionospheric Effects on Network-RTK A part of the atmosphere is ionized by the UV radiation from the Sun. This part is often referred to as the ionosphere. The resulting free electrons influence the GNSS signals as they propagate through the ionosphere. We have studied how the spatial variations of electron density in the ionosphere affect measurements with network-RTK. The aim is to predict wha...

Abstract This paper analyzes candidate schemes for PPP/PPP-RTK (precise point positioning/real-time kinematic) data authentication. Asymmetric are proposed based on existing standards and compatible with GNSS messages. Post-quantum cryptographic signatures also reviewed discussed. Two selected analysis: digital signature (DS) ECDSA, delayed disclosure (DD) a hybrid scheme using the TES...

Mouse developmental kinase 4 (MDK4), a novel receptor tyrosine kinase (RTK), was identified via degenerate primer screening of mouse embryo cDNA. The mRNA encoding this RTK was found only in skeletal muscle of mouse embryos and the maternal decidua. Northern blot analysis predicted an mRNA transcript size of 6.1 kb. The amino acid sequence is most closely related to Torpedo RTK. Analysis of mRN...