نتایج جستجو برای: روش mcr

تعداد نتایج: 371504  

Journal: :Journal of Systems and Software 2021

Modern Code Review (MCR) is a widely known practice of software quality assurance. However, the existing body knowledge MCR currently not understood as whole. Our goal to identify state art on MCR, providing structured overview and an in-depth analysis research done in this field. We performed systematic literature review, selecting publications from four digital libraries. A total 139 papers w...

2016
José R. Mediavilla Amee Patrawalla Liang Chen Kalyan D. Chavda Barun Mathema Christopher Vinnard Lisa L. Dever Barry N. Kreiswirth

UNLABELLED Colistin is increasingly used as an antibiotic of last resort for the treatment of carbapenem-resistant Gram-negative infections. The plasmid-borne colistin resistance gene mcr-1 was initially identified in animal and clinical samples from China and subsequently reported worldwide, including in the United States. Of particular concern is the spread of mcr-1 into carbapenem-resistant ...

2006
BRIAN ROY KEITH M. SMITH

The relationship between a tree's crown radius and diameter at breast height (DBH) has a variety of uses including forest competition studies, tree crown densities, spacing and stoclung relationships, wildlife habitat suitability models, and tree volume estimations. Estimating DBH from mean crown radius (MCR) is of interest to natural resource managers because MCR can be estimated from high res...

Journal: :Antimicrobial agents and chemotherapy 2016
Thongpan Leangapichart Philippe Gautret Philippe Brouqui Ziad Mimish Didier Raoult Jean-Marc Rolain

Aplasmid-mediated transferable colistin resistance gene, mcr-1, was recently described in China (1) and was rapidly reported in several other countries (2). The spread of the mcr-1 gene was not only reported in Escherichia coli but also associated with other Enterobacteriaceae species isolated from human clinical samples, farm animals, and travelers (2, 3). However, whether or not the mcr-1 gen...

Journal: :Nagoya journal of medical science 1987
T Ishiguro Y Sato Y Oshida K Yamanouchi M Okuyama N Sakamoto

Tissue sensitivity to exogenous insulin was determined in 10 obese diabetic patients, in 15 patients with simple obesity, and in 28 non·obese controls. Eight of the obese diabetics and five of the patients with simple obesity underwent dietary restriction (1,000-1,600 kcal/day) and physical training for eight weeks. Insulin sensitivity was evaluated by the euglycemic insulin clamp technique for...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2004
Christine A Iacobuzio-Donahue Jason Song Giovanni Parmiagiani Charles J Yeo Ralph H Hruban Scott E Kern

PURPOSE AND EXPERIMENTAL DESIGN The mutational spectrum of MADH4 (DPC4/SMAD4) opens valuable insights into the functions of this protein that confer its tumor-suppressive nature in human tumors. We present the MADH4 genetic status determined on a new set of pancreatic, biliary, and duodenal cancers with comparison to the mutational data reported for various tumor types. RESULTS Homozygous del...

2009
O. Caliskaner

Several innovative filtration technologies have been developed in the last two decades to decrease the backwash requirements, to increase the water production efficiency, and to improve the operational and design conditions. The Compressible Medium Filter (CMF) also known as the “Fuzzy Filter” involves the use of a synthetic compressible fiber (polyvaniladene) porous material as the filtering m...

Journal: :The Journal of biological chemistry 2006
Andreas Breit Katharina Wolff Hermann Kalwa Hubertus Jarry Thomas Büch Thomas Gudermann

Agouti-related protein (Agrp), one of the two naturally occurring inverse agonists known to inhibit G protein-coupled receptor activity, regulates energy expenditure by decreasing basal and blocking agonist-promoted melanocortin receptor (MCR) signaling. Here we report that, in addition to its inverse agonistic activities, Agrp exhibits agonistic properties on the endocytosis pathway of melanoc...

Journal: :The Journal of clinical investigation 2007
Ruben Nogueiras Petra Wiedmer Diego Perez-Tilve Christelle Veyrat-Durebex Julia M Keogh Gregory M Sutton Paul T Pfluger Tamara R Castaneda Susanne Neschen Susanna M Hofmann Philip N Howles Donald A Morgan Stephen C Benoit Ildiko Szanto Brigitte Schrott Annette Schürmann Hans-Georg Joost Craig Hammond David Y Hui Stephen C Woods Kamal Rahmouni Andrew A Butler I Sadaf Farooqi Stephen O'Rahilly Françoise Rohner-Jeanrenaud Matthias H Tschöp

Disruptions of the melanocortin signaling system have been linked to obesity. We investigated a possible role of the central nervous melanocortin system (CNS-Mcr) in the control of adiposity through effects on nutrient partitioning and cellular lipid metabolism independent of nutrient intake. We report that pharmacological inhibition of melanocortin receptors (Mcr) in rats and genetic disruptio...

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