Analysis of phospholipids was performed using a liquid chromatographic separation with two mass spectrometers in parallel providing electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) data simultaneously from a triple quadrupole instrument and a single quadrupole instrument, respectively. The output from UV-Vis and evaporative light scattering detectors were also a...

Understanding the molecular basis for phenotypic differences between humans and other primates remains an outstanding challenge. Mutations in non-coding regulatory DNA that alter gene expression have been hypothesized as a key driver of these phenotypic differences. This has been supported by differential gene expression analyses in general, but not by the identification of specific regulatory ...

The ability to discover regulatory sequences that control bone-related genes during development has been greatly improved by massively parallel sequencing methodologies. To expand our understanding of cis-regulatory regions critical to the control of gene expression during osteoblastogenesis, we probed the presence of open chromatin states across the osteoblast genome using global DNase hyperse...

OBJECTIVE The purposes of this study were to evaluate the prevalence, types, and locations of Modic changes (MCs) in the thoracic spine in a large number of subjects, and to investigate the relation between the distributions of MCs and disc herniations (DHs) in the thoracic spine. METHODS Two experienced musculoskeletal radiologists assessed the presence of MCs and DHs by consensus in the tho...

Despite the considerable breakthrough in district heating systems (DHS) globally, there is not yet any policy on developing this technology Iran. This country has a high range of energy demand, while renewable energies play minor role its supply chain. Furthermore, world going through transition towards resources, which currently consist only 10% total mix. As first contribution area, paper aim...

Abstract Aim Subtrochanteric femoral fractures are said to occur in the 5cm of bone immediately distal lesser trochanter. This study aims compare peri-operative outcome measures patients with subtrochanteric treated either an IMN, or alternative construct, dynamic hip screw (DHS). Method A retrospective review all presenting our institution between October 2014 and May 2019 was performed. All w...

To view the full product, including the scope and methodology, click on the link above. For more information, contact David Powner at (202) 512-9286 or [email protected]. As the focal point for critical infrastructure protection (CIP), the Department of Homeland Security (DHS) has many cybersecurity-related roles and responsibilities that we identified in law and policy (see table below for 13 ke...

The spiral blade modification of the Dynamic Hip Screw (DHS) was designed for superior biomechanical fixation in the osteoporotic femoral head. Our objective was to compare clinical outcomes and in particular the incidence of loss of fixation. In a series of 197 consecutive patients over the age of 50 years treated with DHS-blades (blades) and 242 patients treated with conventional DHS (screw) ...

BACKGROUND As many other European healthcare systems the Danish healthcare system (DHS) has targeted chronic condition care in its reform efforts. Benchmarking is a valuable tool to identify areas for improvement. Prior work indicates that chronic care coordination is poor in the DHS, especially in comparison with care in Kaiser Permanente (KP), an integrated delivery system based in the United...

Oral methotrexate (MTX) is a highly effective drug for the treatment of severe psoriasis. A limitation of this treatment is its potential hepatotoxicity. In the present prospective study the value of dynamic hepatic scintigraphy (DHS) and serum aminoterminal propeptide of type III procollagen (PIIINP) were investigated as screening methods for early detection of MTX-induced hepatic damage. Thes...