The combined influence of TAS2R38 genotype and PROP phenotype on oral sensations is still to be clarified. present work investigates their the intensity basic tastes somatosensory stimuli (capsaicin, aluminium sulphate), using a large cohort 1117 individuals. possible influences gustin fungiform papillae density were also assessed. was mainly associated with AVI/AVI individuals reporting lowest...

The options framework provides a concrete way to implement and reason about temporally extended actions. Existing literature has demonstrated the value of planning with options empirically, but there is a lack of theoretical analysis formalizing when planning with options is more efficient than planning with primitive actions. We provide a general analysis of the convergence rate of a popular A...

This paper deals with approximate value iteration (AVI) algorithms applied to discounted dynamic programming (DP) problems. For a fixed control policy, the span semi-norm of the so-called Bellman residual is shown to be convex in the Banach space of candidate solutions to the DP problem. This fact motivates the introduction of an AVI algorithm with local search that seeks to minimize the span s...

Travel time has been identified as an important variable to evaluate the performance of a transportation system. Based on the travel time prediction, road users can make their optimal decision in choosing route and departure time. In order to utilize adequately the advanced data collection methods that provide realtime different types of information, this paper is aimed at a novel approach to t...

Abstract This work studies the influence of a vibration isolator on response flexible base structure. Two strategies are compared: passive and active isolation (PVI, AVI). Although multiple advantages AVI over PVI techniques well known, their effect in structure has not to date been compared. interaction an important role performance general control system, especially when system is only or the...

1Division of Cardiovascular Surgery, University Hospital Zürich, Rämistrasse 100, 8091 Zürich, Switzerland 2Department of Radiology, University Hospital Zürich, Rämistrasse 100, 8091 Zürich, Switzerland 3Division of Cardiology, University Hospital Zürich, Rämistrasse 100, 8091 Zürich, Switzerland 4Computer Vision Laboratory, Swiss Federal Institute of Technology (ETH) Zürich, Sternwarstrasse 7,...

Abstract Background The US FDA expanded the approval of ceftazidime-avibactam (CAZ-AVI) to include pediatric patients aged ≥ 3 months in 2019. We evaluated vitro activities CAZ-AVI, ceftolozane-tazobactam (C-T), meropenem-vaborbactam (MEM-VAB), imipenem-relebactam (IMI-REL), and comparators against Enterobacterales (ENT; n=2,391) P. aeruginosa (PSA; n=414) isolates causing infection from medica...

The ribosome is one of the major targets for therapeutic antibiotics; however, the rise in multidrug resistance is a growing threat to the utility of our current arsenal. The orthosomycin antibiotics evernimicin (EVN) and avilamycin (AVI) target the ribosome and do not display cross-resistance with any other classes of antibiotics, suggesting that they bind to a unique site on the ribosome and ...

This article presents improvements in the segmentation module, feature extraction module, and the classification module of a low-cost automated visual inspection (AVI) system for wood defect classification. One of the major drawbacks in the low-cost AVI system was the erroneous segmentation of clear wood regions as defects, which then introduces confusion in the classification module. To reduce...

OBJECTIVES The study aimed to evaluate 1-year outcomes of the multicentre PREVAIL transapical (TA) study of TA-aortic valve implantation (AVI) in high-risk patients. METHODS From September 2009 to August 2010, a total of 150 patients, aged 81.6 ± 5.8 years, 40.7% female, were included at 12 European TA-AVI experienced sites. Patients received 23 (n = 36), 26 (n = 57) and 29 mm (n = 57) second...