Numerous methods of management applied in order to obtain higher therapeutic efficacy of drugs with minimum adverse effects include taking advantage of interactions taking place between individual agents. Analgesics are combined with drugs belonging to other therapeutic groups, including, more and more frequently, antiepileptic agents. The influence of oxcarbazepine (10 mg/kg) on the antinocice...

introduction: pain research using animal models is related to ethical concerns, so invertebrates and insects have been recommended by researchers. in the present study, the nociceptive and antinociceptive effects of capsaicin, aspirin, morphine and chili extract were examined using fruit fly (drosophila melanogaster) as an alternative for rodent pain model. methods: stage 3 of larvae and adult ...

Objective: Berberis vulgaris has antioxidant, hepato--renal protective, antibacterial, lipid lowering, anti-inflammatory and antinociceptive activities. The genus Berberis, has another member called Berberisintegerrima which has not been studied for antinociceptive activity and therefore, this study was aimed to examine the antinociceptive effect oftotal extract and alkaloid fractions of Berber...

The present study is a designed protocol for investigation of the analgesic effect of oral and intraperitoneal (i.p.) administration of alcoholic Datura stramonium (DS) seed extract as a rich source of alkaloid substances. Male NMRI rats were divided into control and treatment groups. The treatment rats received different doses of the DS seed extract, which was prepared from alcoholic smashed s...

The present study is a designed protocol for investigation of the analgesic effect of oral and intraperitoneal (i.p.) administration of alcoholic Datura stramonium (DS) seed extract as a rich source of alkaloid substances. Male NMRI rats were divided into control and treatment groups. The treatment rats received different doses of the DS seed extract, which was prepared from alcoholic smashed s...

[1] Here, I present a new absolute plate motion model of the Earth’s surface, determined from the alignment of present-day surface motions with 474 published shear wave (i.e., SKS) splitting orientations. When limited to oceanic islands and cratons, splitting orientations are assumed to reflect anisotropy in the asthenosphere caused by the differential motion between lithosphere and mesosphere....

هدف: هدف اصلی این نوشتار، تأملی بر دستاوردهای علمی استادان مدیریت آموزشی در دانشگاه‌های دولتی ایران با تأکید شناخت جهت‌گیری‌های پژوهشی آنان می‌باشد.مواد و روش‌ها: برای دستیابی به از روش پژوهش اسنادی نوع مرور نظام‌مند به‌منظور بازخوانی پژوهش‌های انجام شده توسط بهره گرفته شد. پس مراجعه صفحه شخصی حدود 170 عضو هیئت وابسته گروه‌های دارای رشته جمله گروه علوم تربیتی، پایش نمونه براساس نمونه‌گیری هدفمن...

The present study was performed on rats with experimental mononeuropathy induced by left common sciatic nerve loose ligation. Unilateral sciatic nerve loose ligation induced decreases of the hindpaw withdrawal latency to the hot-plate test, cold-plate test and the Randall Selitto test. Sciatic nerve loose ligation induced hyperesponsiveness to touch at room temperature also. Intrathecal adminis...