The Centers for Disease Control and Prevention has established 10 Global Disease Detection (GDD) Program regional centers around the world that serve as centers of excellence for public health research on emerging and reemerging infectious diseases. The core activities of the GDD Program focus on applied public health research, surveillance, laboratory, public health informatics, and technical ...

BACKGROUND Investigation of patients, particularly children, with unexplained global developmental delay (GDD)/learning disability (LD) has been challenging due to a lack of clear guidance from specialised centres. Limited knowledge of rare diseases and a poor understanding of the purpose or limitations of appropriate investigations have been some of the principal reasons for this difficulty. ...

Generalized Steiner systems GS(2, k, v, g) were first introduced by Etzion and used to construct optimal constant weight codes over an alphabet of size g + 1 with minimum Hamming distance 2k − 3, in which each codeword has length v and weight k. As to the existence of a GS(2, k, v, g), a lot of work has been done for k = 3, while not so much is known for k = 4. The notion k-GDD was first introd...

INTRODUCTION Global developmental delay (GDD) affects 1%-3% of the population of children under 5 years of age, making it one of the most common conditions presenting in paediatric clinics; causes are exogenous, genetic (non-metabolic) or genetic (metabolic). Recent advances in biotechnology and genetic testing mean that the investigations available to perform for children under 5 years are inc...

Purpose Glaucoma drainage device (GDD) implantation can lead to corneal decompensation. We evaluated changes over time in oxygen tension and in the metabolic environment of the aqueous humor after GDD implantation in the rabbit eye. Methods Ahmed Glaucoma Valves were implanted in the left eyes of eight male New Zealand white rabbits. Right eyes were used as a control. Oxygen tension was measu...

AIM Microarray technology has a significantly higher clinical yield than karyotyping in individuals with global developmental delay (GDD). Despite this, it has not yet been routinely implemented as a screening test owing to the perception that this approach is more expensive. We aimed to evaluate the effect that replacing karyotype with array-based comparative genomic hybridization (aCGH) would...

PURPOSE To evaluate the results and long-term complications of glaucoma drainage devices (GDD) in paediatric patients (0-15 years). METHODS Retrospective cohort study was conducted on 17 implanted glaucoma drainage devices from July 1994 to April 2007 in 14 patients (17 eyes). In two patients (3 eyes) a Molteno GDD (MGDD) was implanted, and in 12 patients (14 eyes) an Ahmed GDD (AGDD) was use...

This supplement of the Journal provides a compendium of epidemiologic, clinical, and laboratory data to address gaps in knowledge regarding acute respiratory illness associated with respiratory syncytial virus (RSV) in countries participating in the International Emerging Infections Program and the Influenza Program of the Global Disease Detection (GDD) network of the US Centers for Disease Con...

بررسی آزمایشگاهی غلظت مهارکنندگی عصاره‌های متانولی و اتانولی گیاه کاکوتی قان‌تپر بر رشد باکتری استرپتوکوکوس موتانس قارچ کاندیدا آلبیکنس