Normal human colonic luminal (NH(4)(+)) concentration ([NH(4)(+)]) ranges from approximately 10 to 100 mM. However, the nature of the effects of NH(4)(+) on transport, as well as NH(4)(+) transport itself, in colonic epithelium is poorly understood. We elucidate here the effects of apical NH(4)(+) on cAMP-stimulated Cl(-) secretion in colonic T84 cells. In HEPES-buffered solutions, 10 mM apical...

The ammonia-oxidizing archaea have recently been recognized as a significant component of many microbial communities in the biosphere. Although the overall stoichiometry of archaeal chemoautotrophic growth via ammonia (NH(3)) oxidation to nitrite (NO(2)(-)) is superficially similar to the ammonia-oxidizing bacteria, genome sequence analyses point to a completely unique biochemistry. The only ge...

BACKGROUND Many newborn babies experience low blood glucose concentrations, a condition referred to as neonatal hypoglycaemia (NH). The effect of NH on visual development in infancy and childhood is of interest because the occipital lobes, which include the primary visual cortex and a number of extrastriate visual areas, may be particularly susceptible to NH-induced injury. In addition, a numbe...

Nakhoul, Nazih L., Kathleen S. Hering-Smith, Solange M. Abdulnour-Nakhoul, and L. Lee Hamm. Transport of NH3/NH4 1 in oocytes expressing aquaporin-1. Am J Physiol Renal Physiol 281: F255–F263, 2001.—The aim of this study was to determine whether expressing aquaporin (AQP)-1 could affect transport of NH3. Using ion-selective microelectrodes, the experiments were conducted on frog oocytes (cells ...

In low-temperature flash photolysis of NH3/O2/N2 mixtures, the NH2 consumption rate and product distribution is controlled by reactions + HO2 → products (R1), H (+M) NH3 (R...

Root growth in higher plants is sensitive to excess ammonium (NH(4)(+)). Our study shows that contact of NH(4)(+) with the primary root tip is both necessary and sufficient to the development of arrested root growth under NH(4)(+) nutrition in Arabidopsis. We show that cell elongation and not cell division is the principal target in the NH(4)(+) inhibition of primary root growth. Mutant and exp...

In the Author Contributions section, Nathalie J. M. van Hees (NH), Erik J. Giltay (EG), Thomas Puvill (TP), Nadine Janssen (NJ), and Willem van der Does (WD) all should be listed as one of the persons who wrote the paper. The correct contributions are: Conceived and designed the experiments: NH EGWD. Performed the experiments: NH TP NJ. Analyzed the data: NH EG TP NJ WD ST. Contributed reagents...

Ardis L. Olson, MD;1 Cecelia A. Gaffney, MEd;1 Viking A. Hedberg, MD, MPH;2 Wendy Gladstone, MD;3 Sam Dugan, MD;4 Robert Mathes, MD;5 Paul Reiss, MD6 1Dartmouth Medical School, Hanover, NH 2Plymouth Pediatrics, Dartmouth-Hitchcock Clinic, Plymouth, NH 3Exeter Pediatric Associates, Exteter, NH 4Bedford Pediatrics, Dartmouth-Hitchcock Clinic, Bedford, NH 5Abenaki Family Physicians, Wolfeboro Fall...

Rhbg is a membrane glycoprotein that is involved in NH(3)/NH(4)(+) transport. Several models have been proposed to describe Rhbg, including an electroneutral NH(4)(+)/H(+) exchanger, a uniporter, an NH(4)(+) channel, or even a gas channel. In this study, we characterized the pH sensitivity of Rhbg expressed in Xenopus oocytes. We used two-electrode voltage clamp and ion-selective microelectrode...

Negative impacts on the environment, bird well-being, and farm worker health indicate the need for abatement strategies for poultry litter NH(3) generation. Type of bedding affects many parameters related to poultry production including NH(3) losses. In a randomized complete block design, 3 trials compared the cumulative NH(3) volatilization for laboratory-prepared litter (4 bedding types mixed...