African Americans are at increased risk of type 2 diabetes and many diabetes complications. We have carried out a genome-wide scan for African American type 2 diabetes using 638 affected sibling pairs (ASPs) from 247 families ascertained through impaired renal function to identify type 2 diabetes loci in this high-risk population. Of the 638 ASPs, 210 were concordant for diabetes with impaired ...

This prospectus analyzes the potential determinants of Chinese non-performing loan (NPL) ratio in banking sector and its implications using panel data from different banks in China. By incorporating both bank specific factors and macro variables, it shows domestic credit growth rate, bank profitability measures and bank ownership play important roles in determining NPL ratio. Analysis of propor...

Quotient Image (QI) algorithm has been widely used in face recognition and rerendering under varying illumination conditions. One of the inaccuracies of QI algorithm is the assumption of ‘‘Ideal Class’’, that all faces have the same surface normal (3D shape). However, in practice this assumption is often not true. To reduce the inaccuracy, the Non-Ideal Class Non-Point Light source QI (NIC-NPL-...

To investigate the relationship between 12 candidate genes responsible for water regulation, sodium metabolism and membrane ion transport and essential hypertension (EH) in the Chinese. Linkage analysis of EH was performed in 95 Chinese nuclear families including 477 subjects using a technique of fluorescence-based gene scanning with 12 microsatellite markers. Markers were selected on the chrom...

Calculations of the significance of results from linkage analysis can be performed by simulation or by theoretical approximation, with or without the assumption of perfect marker information. Here we concentrate on theoretical approximation. Our starting point is the asymptotic approximation formula presented by Lander and Kruglyak (1995, Nature Genetics, 11, 241--247), incorporating the effect...

OBJECTIVES To identify the loci involved in nonsyndromic cleft lip with or without cleft palate (NSCL/P) in Northern Chinese people in Shenyang by using genomewide and interaction linkage scan. METHODS Two multiplex families in Shenyang from North China were ascertained through probands with NSCL/P. Blood of every member was drawn for DNA extraction and analysis. Genotypes were available for ...

Credit risk assessment and, in particular, nonperforming loan (NPL) projection are a crucial part of macro-stress tests. These tests are based on macroeconomic assumptions in order to provide common scenarios for all financial institutions participating in such an exercise. However, due to limited data availability, short time series and structural breaks, especially in emerging markets, it is ...

Pandemi Covid-19 yang menerpa Indonesia sangat berdampak pada berbagai sektor tak terkecuali jasa keuangan khususnya perbankan. Salah satu indikator digunakan dalam mengukur kinerja perbankan adalah non performing loan (NPL). Penelitian ini bertujuan untuk mengetahui bank pembangunan daerah terdaftar di Bursa Efek terkait dampak pandemi menggunakan proxy NPL. Hasil penelitian menunjukkan bahwa ...

Linkage results suggest that the region of chromosome 7 containing the leptin gene cosegregates with extreme obesity; however, leptin coding region mutations are rare. To investigate whether the leptin flanking sequence and/or a larger 40-cM region (7q22.1-7q35) contributes to obesity, we genotyped individuals from 200 European American families segregating extreme obesity and normal weight (1,...