Glucocorticoid remediable aldosteronism (GRA), an autosomal dominant cause of primary aldosteronism, has been described as resulting in severe hypertension with premature death from stroke. We describe two new large pedigrees which include subjects who have the abnormal chimaeric gene strongly linked to GRA. The majority of affected members, who have only mild hypertension and normal biochemist...

In machine learning, multiclass or multi-label classification is the special case within statistical classification of assigning one of several class labels to an input object. The multiclass problem is more complex than binary classification and less researched problem. In biology promoter is the DNA region where the transcription initiation takes place. Reliable recognition of promoter region...

Evaluating and enhancing resilience in water infrastructure is a crucial step towards more sustainable urban water management. As a prerequisite to enhancing resilience, a detailed understanding is required of the inherent resilience of the underlying system. Differing from traditional risk analysis, here we propose a global resilience analysis (GRA) approach that shifts the objective from anal...

Condition diagnosis of multiple bearings system is one of the requirements in industry field, because bearings are used in many equipment and their failure can result in total breakdown. Conditions of bearings commonly are reflected by vibration signals data. In multiple bearing condition diagnosis, it will involve many types of vibration signals data; thus, consequently, it will involve many f...

1.1. General formalism and basic examples. Let A = ⊕ i>0Ai be a graded algebra equipped with a Poisson bracket {·, ·} that has degree −1 because {Ai, Aj} ⊂ Ai+j−1. By a quantization of A one means a pair (A, ι), where • A is a filtered associative unital algebra A = ∪ i>0 A6i. • ι : grA → A is an isomorphism of graded Poisson algebras. Recall that grA := ⊕ i>0 A6i/A6i−1 is a graded algebra. Tha...

Generic Router Assist (GRA) is a network-based service that enables end-to-end multicast transport protocols to take advantage of information distributed across the network elements in a given multicast distribution tree. The service consists of a canonical set of simple functions which network elements may apply to selected packets in the transport session as they traverse the distribution tre...

Taiwan is affected by three primary types of natural disaster: typhoons, earthquakes, and floods. Natural disasters in Taiwan can cause human causalities and loss of housing. Therefore, a method for evaluating the severity of losses caused by natural disasters would be beneficial for disaster management institutes in Taiwan when developing further supply chain management (SCM) strategies. To ev...

The aim of this study was to investigate the wear of four nanofilled resin composites using simulated toothbrushing for 50,000 cycles with calcium carbonate slurry. The depth of abrasion and roughness (Ra) were measured after each 10,000 brushing cycle. The surface texture of the worn samples was examined by SEM.The wear depths of the nanofill Filtek Supreme XT (FIL), the nanohybrides Grandio (...

In this paper, wire electrical discharge machining of D3 tool steel is studied. Influence of pulse-on time, pulse-off time, peak current and wire speed are investigated for MRR, dimensional deviation, gap current and machining time, during intricate machining of D3 tool steel. Taguchi method is used for single characteristics optimization and to optimize all four process parameters simultaneous...