نتایج جستجو برای: آنزیم taq

تعداد نتایج: 13056  

Journal: :Nucleic acids research 1995
E Grimm P Arbuthnot

The polymerase chain reaction (PCR) and dideoxy DNA sequencing are frequently used techniques of molecular biology which utilise DNA polymerases. The high temperatures required for PCR necessitate a thermostable enzyme for DNA amplification, and DNA polymerase derived from the thermophilic microorganism, Thermus aquaticus, is used most commonly. The high optimal polymerisation temperature of th...

Journal: :The European respiratory journal 1998
R Mahadeva R C Westerbeek D J Perry J U Lovegrove D B Whitehouse N R Carroll R I Ross-Russell A K Webb D Bilton D A Lomas

Cystic fibrosis (CF) is characterized by progressive and ultimately fatal pulmonary disease although there are notable variations in clinical features. This heterogeneity is thought to lie outside the cystic fibrosis transmembrane regulator (CFTR) gene locus and may stem from deficiencies in the antiproteinase screen that protects the lung from proteolytic attack. One hundred and fifty seven pa...

2017
Marcin Olszewski Marta Śpibida Maciej Bilek Beata Krawczyk

DNA polymerases are present in all organisms and are important enzymes that synthesise DNA molecules. They are used in various fields of science, predominantly as essential components for in vitro DNA syntheses, known as PCR. Modern diagnostics, molecular biology and genetic engineering need DNA polymerases which demonstrate improved performance. This study was aimed at obtaining a new NeqSSB-T...

Journal: :The Journal of biological chemistry 2004
Derek L Ho W Malcolm Byrnes Wu-Po Ma Yuan Shi David J E Callaway Zimei Bu

The DNA polymerase I from Thermus aquaticus (Taq polymerase) performs lagging-strand DNA synthesis and DNA repair. Taq polymerase contains a polymerase domain for synthesizing a new DNA strand and a 5'-nuclease domain for cleaving RNA primers or damaged DNA strands. The extended crystal structure of Taq polymerase poses a puzzle on how this enzyme coordinates its polymerase and the nuclease act...

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