نتایج جستجو برای: آلوری اکتیویتی سلول nk
تعداد نتایج: 36183 فیلتر نتایج به سال:
Transient stimulation with substance P (SP) induces endocytosis and recycling of the neurokinin-1 receptor (NK(1)R). The effects of sustained stimulation by high concentrations of SP on NK(1)R trafficking and Ca(2+) signaling, as may occur during chronic inflammation and pain, are unknown. Chronic exposure to SP (100 nm, 3 h) completely desensitized Ca(2+) signaling by wild-type NK(1)R (NK(1)Rw...
Shark cartilage is considered as a natural dietary supplement consisting of anti-angiogenic, immunostimulatory, and anti-inflammatory characteristics. Therefore, this study was designed to inspect the possibility that whitecheek shark (Carcharhinus dussumieri) cartilage proteins motivate expression of NKG2D, CXCR3, NKP46, and NKP44 receptors on natural killer cells and their activities against ...
زمینه و هدف: ccr5 یکی از مهمترین گیرنده های کموکاینی است که در فراخواندن سلول های ایمنی اختصاصی (نظیر: سلول های t سایتوتوکسیک و سلول های nk) ضد ویروسی به کبد نقش دارد. ccr5-?32 و (c/t) ccr5-59353دو پلی مرفیسم بسیار مهم در ژن ccr5 هستند و در برخی مطالعات گزارش گردیده که ممکن است با پاکسازی و یا تداوم عفونت مزمن hbv مرتبط باشند. لذا این مطالعه جهت بررسی دو پلی مرفیسم مذکور در بیماران ایرانی با هد...
مدل های ریاضی برهمکنش ایمنی با سرطان چارچوبی را برای بررسی دقیق تر و تعین رژیم درمانی موثر با حداقل اثرات جانبی داروئی فراهم می کند. در این تحقیق ما مدلی را برای بررسی انتخاب کردیم که در سال 2005 توسط پیلیس و همکارانش برای درمان سرطان بدخیم پوست به روش واکسن درمانی ارائه شد. این مدل بر روی نقش سلول های ایمنی nk وcd8+ در مبارزه با سلول های سرطانی پوست متمرکز شده است. در این مدل از معادلات دیفران...
Development of natural killer (NK) cells is thought to depend on interactions between NK progenitors and the bone marrow (BM) microenvironment; however, little is known about the molecular signals involved. Here we show that lymphotoxin (LT) provides an important signal for the development of both NK cells and NK/T cells. LTalpha-/- mice show marked reduction in splenic and BM NK and NK/T cell ...
Background Nasopharyngeal carcinoma, common in Southeast Asia, is mainly a non-keratinizing, squamous cell carcinoma (NK-NPC) and clinically heterogeneous. Methods Herein, we analyzed three human gene expression microarray datasets characterizing 81 NK-NPC tumors and 21 normal nasopharyngeal (NP) tissues to identify molecular subtypes of NK-NPC. In one of the datasets, QRT-PCR measurement of ex...
The study object is a prototype of composite bridge prestressed concrete beam with length 42.0 m for road desks perception impact from motor vehicles in the form A14, NK-120 and NK-180 loads.
The base of this study has been demonstrated the use of different drugs and dosages on different tumour cell lines and finally the effect of these drugs on natural killerllimphokine activated killer (NK/LAK) Killing. Tumour cells as target , mononeuclear cell activated with inter leukin-2(LAK) as effector, anti cancer drugs like tamoxifen , pentoxifylline , cycloheximide and cisplatin as stimul...
The precise locations of neurokinin (NK)-1 and NK-2 receptors in human airways, and their role in airway inflammatory diseases, have not been carefully examined. To determine the distribution of NK-1 and NK-2 receptors in human central airways, and to determine whether their distribution was different in smokers, we examined surgical specimens from patients undergoing lung resection for limited...
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