Infectious bovine rhinotracheitis (IBR) is a highly infectious disease of cattle caused by bovine herpesvirus 1 (BHV-1) that causes considerable economic losses to the dairy and beef industry. This report describes the results of two surveys in which prevalence of serum antibodies against BHV-1 in Galicia (NW Spain) was determined. The first was performed on the entire cattle population of the ...

The effect of dexamethasone on infectious bovine rhinotracheitis virus (Bovine herpesvirus 1: BHV 1) was studied by measuring the mean plaque size produced by eight virus strains under two concentrations of dexamethasone phosphate (0.1 and 1 mM). Dexamethasone induced a significant reduction of the mean plaque size, whatever the strain used. Some differences were noted between the BHV 1 strains...

We investigated the effect of supplemental vitamin E on antibody titer against bovine herpesvirus-1 (BHV-1) in Japanese Black calves after vaccination with modified live virus. Thirty calves kept at the same farm were studied. They were divided into two groups; fifteen calves received 300 IU/day of vitamin E orally from 1 to 3 months of age (VE Group), and the other fifteen calves did not recei...

Bovine herpesvirus-1 (BHV-1) is associated with a various respiratory and genital clinical manifestations in cattle. It belongs to alphaherpesvirinae family with double stranded DNA genome of 140 kb size. As other herpesviruses, BHV-1 also transcribes viral proteins into three kinetic classes namely immediate early (IE), early (E) and late (L). Transcription of these genes is dependent on sever...

یکی از مهم‌ترین مدهای حمل‌ونقل عمومی شبکة مترو است که تأثیر بسزایی در کاهش ترافیک و آلودگی هوا دارد. ازدیگرسو، با توجه به هزینه‌های سرسام‌آور راه‌اندازی مترو، توسعة مرحله‌به‌مرحله بهره‌برداری یک خط اجرای خطوط دیگر به‌دست مدیران شهری مورد است. بنابراین، هدف این تحقیق بررسی میزان دسترسی متروی اصفهان افق 1410، رویکرد عدالت مکانی، دو جنبة افقی عمودی پنج طبقة اجتماعی، استفاده شاخص‌های ضریب جینی، منح...

Herpesviruses enter cells by a yet poorly understood mechanism. We visualized the crucial steps of the entry pathway of bovine herpesvirus 1 (BHV-1) and BHV-5 by transmission and scanning electron microscopy, employing cryotechniques that include time monitoring, ultrarapid freezing, and freeze substitution of cultured cells inoculated with virus. A key step in the entry pathway of both BHV-1 a...

The aim of the present work was to evaluate the prevalence and efficacy of IBR control measures in selected cattle herds in Lithuania. Serological investigations in 1997 2007 years (34600 blood sera samples tested) showed that BHV-1 infection mostly detected in cows (33.86%), less in heifers (8.77%) and in bulls group (1.69%). In majority of the cases seropositive bulls were detected in quarant...

BACKGROUND Bovine respiratory disease (BRD) remains among the leading causes of death of cattle internationally. The objective of this study was to identify risk factors associated with exposure to BRD pathogens during the peri-weaning period (day (d)-14 to d 14 relative to weaning at 0) in dairy bull calves using serological responses to these pathogens as surrogate markers of exposure. Clinic...

To determine the potential of replication-competent (E3-deleted) bovine adenovirus-3 (BAV-3) as a delivery system for vaccine antigens in calves, we evaluated the ability of recombinant BAV-3 expressing different forms of of bovine herpesvirus-1 (BHV-1) glycoprotein gD to protect against BHV-1 infection in calves that had pre-existing BAV-3 specific antibodies. Three- to four-month-old calves, ...

Bovine herpesvirus 5 (BHV-5) is a neurovirulent alphaherpesvirus that causes fatal encephalitis in calves. In a rabbit model, the virus invades the central nervous system (CNS) anterogradely from the olfactory mucosa following intranasal infection. In addition to glycoproteins E and I (gE and gI, respectively), Us9 and its homologue in alphaherpesviruses are necessary for the viral anterograde ...