OBJECTIVE Assessed the convergent and discriminant validity of a water load symptom provocation test (WL-SPT) in creating visceral sensations similar to the naturally occurring sensations experienced by children with functional abdominal pain. METHODS Participants were pediatric patients with functional abdominal pain (N = 110) and healthy school children (N = 120) between the ages of 8 and 1...

A solid-pseudopapillary tumor (SPT) of the pancreas is known as a low grade malignant tumor with a good prognosis; therefore, surgical intervention is necessary. A 14-year-old boy presented with a large pancreatic SPT and three hepatic metastases. The patient and his family refused surgery. Two serial follow-up CT scans over a period of 13 years demonstrated almost complete disappearance of the...

Individuals with Spinal Cord Injury (SCI), perform Sitting Pivot Transfer (SPT) motion around fifteen times a day using upper extremities. It can lead to upper limbs pain and often shoulder complications. In this paper, we investigate the influence of Functional Electrical Stimulation (FES) on SPT motion of a paraplegic person. First, we proposed to develop...

Compliance with supportive periodontal therapy (SPT) depends on many factors but is generally poor. We compared SPT compliance among patients with aggressive and chronic periodontitis. This single-center longitudinal observational study enrolled 101 patients with generalized aggressive periodontitis (GAP; n = 52) or generalized chronic periodontitis (GCP; n = 49) to compare SPT compliance. All ...

We have identified mutations in seven unlinked genes (SPT genes) that affect the phenotypes of Ty and delta insertion mutations in the 5' noncoding region of the HIS4 gene of S. cerevisiae. Spt mutants were selected for suppression of his4-912 delta, a solo delta derivative of Ty912. Other Ty and delta insertions at HIS4 are suppressed by mutations in some but not all of the SPT genes. Only spt...

Maintenance of sphingolipid homeostasis is critical for cell growth and programmed cell death (PCD). Serine palmitoyltransferase (SPT), composed of LCB1 and LCB2 subunits, catalyzes the primary regulatory point for sphingolipid synthesis. Small subunits of SPT (ssSPT) that strongly stimulate SPT activity have been identified in mammals, but the role of ssSPT in eukaryotic cells is unclear. Cand...

allergy history. Methods: 42 patients with suspected beta-lactam hypersensitivity reactions were evaluated at a drug allergy clinic at a tertially allergy center. Skin prick tests (SPT) with major determinants (PPL), minor determinants (MDM), penicillin G, ampicillin, amoxicillin, intradermal tests (ID) and specific IgE determination were done. If all tests were negative, a drug challenge was p...

Hereditary sensory neuropathy type 1 (HSN1) is a dominantly inherited degenerative disorder of the peripheral nerves. HSN1 is clinically and genetically heterogeneous. One form arises from mutations in the gene SPTLC1 encoding long-chain base 1 (LCB1), one of two subunits of serine palmitoyltransferase (SPT), the enzyme catalyzing the initial step of sphingolipid synthesis. We have examined the...

We study (d − 1)-dimensional excitations in the d-dimensional color code that are created by transversal application of the Rd phase operators on connected subregions of qubits. We find that such excitations are the superpositions of electric charges and can be characterized by the fixed-point wave functions of (d − 1)dimensional bosonic symmetry-protected topological (SPT) phases with (Z2)⊗d s...

Serine palmitoyltransferase (SPT) is a first-step enzyme in the sphingolipid biosynthetic pathway. Myriocin is an inhibitor of SPT and suppresses replication of the hepatitis C virus (HCV) replicon. However, it is still unknown whether this SPT inhibitor suppresses HCV replication in vivo. We investigated the anti-HCV effect of myriocin against intact HCV using chimeric mice with humanized live...