Background and Objective: Fatty liver disease occurs due to disturbances in lipid metabolism (increased fat synthesis and halting of catabolism) which eventually leads to the accumulation of large amounts of fat (triglycerides) in liver cells, that if left untreated lead to inflammation and cirrhosis. This study aimed to investigate the effect of concomitant use of HESA-A and atorvastatin on bi...

Introduction: Diabetes is an abnormality in metabolism, which occurs because of hyperglycemia resulting from failure in insulin release, function, or both. This study was conducted to investigate the effect of combined atorvastatin and zinc on serum levels of glucose and insulin and morphology of pancreas in type 1 diabetic rats. Methods: In this experimental study, 40 female Wistar rats were ...

این پایان نامه شامل دو بخش است. در بخش اول یک سیستم دارورسانی جدید برای داروهای سپیروفلاکساسین، اوفلاکساسین و آتورواستاتین با استفاده از بسپارهای هوشمند و نانوذرات مغناطیسی اصلاح شده طراحی شده است. در این بخش که شامل سه فصل است سه حامل دارویی مختلف تهیه و خواص بارگذاری و رهایش داروی آن ها مورد مطالعه قرار گرفت. حامل های تهیه شده به روش های tem، xrd، ft-ir، tga، dsc و تجزیه عنصری شناسایی شدند. ر...

Background and Aim: The present study aimed at investigating the effect of a 12-week aerobic water exercise and atorvastatin on of Atrial Natriuretic Peptide (ANP) and Brain Natriuretic Peptide (BNP) changes in older men with cardiovascular diseases. Materials and Methods: In the current study, 40 patients with cardiovascular disease, aged 50-65yrs, who were volunteers for the research were di...

Background & Aims: Diabetes is the most common endocrine disease associated with impaired glucose and lipid metabolism. The aim of this study was to evaluate the effects of combined atorvastatin and zinc sulfate on blood glucose and lipids in diabetic rats. Materials & Methods: One control group (group NC) and four diabetic groups as diabetic control (group DC), treatment with atorvastatin 20m...