نتایج جستجو برای: α1 receptor
تعداد نتایج: 594913 فیلتر نتایج به سال:
One of the earliest events in the pathogenesis of systemic sclerosis (SSc) is microvasculature damage with intimal hyperplasia and accumulation of cells expressing PDGF receptor. Stimulatory autoantibodies targeting PDGF receptor have been detected in SSc patients and demonstrated to induce fibrosis in vivo and convert in vitro normal fibroblasts into SSc-like cells. Since there is no evidence ...
In the amygdala, GABAergic neurons in the intercalated medial paracapsular cluster (Imp) have been suggested to play a key role in fear learning and extinction. These neurons project to the central (CE) amygdaloid nucleus and to other areas within and outside the amygdala. In addition, they give rise to local collaterals that innervate other neurons in the Imp. Several drugs, including benzodia...
21 Spontaneous hypertensive rats (SHR) are widely used as a model of attention deficit 22 hyperactivity disorder (ADHD) as their ADHD-like behaviors are restored by 23 methylphenidate (MPH). However, a postnatal neural development in SHR is unknown. 24 We performed whole cell patch clamp recordings from locus coeruleus (LC) neurons in 25 neonatal (P 3–5), juvenile (P 21–28) and adult (P 49–56) ...
Dystroglycan is a laminin receptor, which with dystrophins and other components forms the dystrophin-dystroglycan complex. It has an important role in the formation of gliovascular connections, cerebral vascularisation and blood-brain barrier. Dystroglycan consists of two sub-units, α and β. Previous studies demonstrated that the β-dystroglycan immunoreactivity of cerebral vessels temporarily d...
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