I this issue, Arbyn et al (see p. 167) update the evidence about the accuracy of liquid-based cytology compared with conventional cytology, and the results are not encouraging.1 In summary, best evidence suggests that liquid-based cytology does not lead to more disease detection and appears to increase false-positive testing, sobering news given that over 80% of U.S. obstetrician–gynecologists ...

OBJECTIVES Traditionally, urine cytology has been considered as the gold standard for bladder cancer screening. However, new methods are playing new roles in these cases. In order to assess the value of cytology of voided urine we performed one comparative study between cytology and biopsy. METHODS We retrospectively analyzed the results of urine cytology and biopsy follow-up in 109 patients....

Diagnostic cytology is a relatively new science. Cytology (Greek word: kytos = hollow vessel) is the study of individual cells and their intrinsic characteristics and functions. George Papanicolaou is considered the father of exfoliative cytology, but cytology was first used in cutaneous disorders by Tzanck in 1947, for the diagnosis of vesiculo-bullous disorders, particularly herpes simplex. S...

The surgical histology report was the standard for confirming the accuracy of the diagnostic FNA cytology classification. The specificity of the FNA cytology was estimated using two approaches. One was to consider the FNA as a diagnostic test if the FNA specimens were interpreted as suspicious of malignancy or positive for malignancy, and the remaining categories were classified as negative. Th...

OBJECTIVE Since cytology is the examination utilized for the screening of cervical cancer, it is important to determine its correlation with histologic examination, the gold standard in the diagnosis of cervical disease. STUDY DESIGN A retrospective evaluation was made of 431 patients who presented with colposcopic indication for cervical biopsy between 2003 and 2007. RESULTS In 90.8% (289/...

Abstract Aim Risk stratification of thyroid nodules based on ultrasound scan (USS) features using the TIRADS- or U-scale has been widely adopted. However, management decisions for patients whose work-up provide conflicting information, remains challenging. The aim this study was to assess rate malignancy among those with suspicious cytology after USS-evaluation. Methods Retrospective review cli...

BACKGROUND In qualitative diagnosis of bile duct stenosis, single diagnostic measure is difficult to make a correct diagnosis, to combine several diagnostic techniques may be helpful to make an accurate diagnosis. The aim of this study was to evaluate the value of intraductal ultrasonography (IDUS), endoscopic brush cytology and K-ras, P53 gene mutation in the early diagnosis of malignant bilia...

INTRODUCTION We evaluated the UroVysion (Abbott Molecular, IL, USA) fluorescence in situ hybridization (FISH) assay for the diagnosis of urothelial cancer in patients diagnosed with or suspected to have bladder, upper tract urothelial carcinoma (UTUC), and combined upper and lower tract urothelial carcinoma (BC). MATERIALS AND METHODS A single institution retrospective analysis comparing sens...