Drosophila mutants provide an ideal model to study channel-type specificity of ion channel regulation in situ. In this study, the effects of divalent cations on voltage-gated K+ currents were investigated in acutely dissociated central neurons of Drosophila third instar larvae using the whole-cell patch-clamp recording. Our data showed that micromolar Cd2+ enhanced the peak inactivating current...

The present study synthesizes a novel adsorbent by coating Fe3O4 magnetic nanoparticles with amino functionalized mesoporous silica. The FTIR spectrums indicate that silica has been successfully coated on the surface of Fe3O4 and 3-aminopropyl tri methoxysilane compound have been grafted to the surface of silica-coated Fe3O4. The XRD analysis shows the presence of magnetite phase with cubic spi...

The effects of divalent cations (Zn2+, Cd2+, Ca2+, Mg2+) on the cytosol androgen receptor were determined by sedimentation into sucrose gradients. At low ionic strength (25 mM KCl, 50 mM Tris, pH 7.4), Zn2+ (200 microM total, which calculates to 130 nM free Zn2+ in 10 mM mercaptoethanol) causes a shift in the sedimentation coefficient of the rat Dunning prostate tumor (R3327H) cytosol receptor ...

Identifying the metal ions that optimize charge transport and charge density in metal-organic frameworks is critical for systematic improvements in the electrical conductivity in these materials. In this work, we measure the electrical conductivity and activation energy for twenty different MOFs pertaining to four distinct structural families: M2(DOBDC)(DMF)2 (M = Mg2+, Mn2+, Fe2+, Co2+, Ni2+, ...

In this work, two Schiff base ligands Z2a and Z2b derived from 5-aminoisophthalic acid were synthesized their structures characterized by FTIR, 1H(13C) NMR mass spectrometries. The compounds investigated for chemosensor properties towards metal ions [Na+, K+, Al3+, Cr3+, Mn2+, Fe3+, Co2+, Ni2+, Cu2+, Zn2+, Cd2+, Hg2+ Pb2+] examined using colorimetric spectrophotometric methods (UV-Vis absorptio...

A NIR cyanine@imidazole derivative Cy1 was synthesized and evaluated as a metal ion sensor in solution. shown to be very sensitive all ions tested, presenting blue shift the absorption from 668 nm 633 nm, followed by change colour pale green with Zn2+, Cd2+, Co2+, Ni2+ Hg2+ ions. Despite absorption, decrease at (with colourless), well quenching emission intensity 785 were observed for Cu2+ The ...

Given the many roles proposed for Mg2+ in nucleic acids, it is essential to accurately determine their binding modes. Here, we surveyed the PDB to classify Mg2+ inner-sphere binding patterns to nucleobase imine N1/N3/N7 atoms. Among those, purine N7 atoms are considered to be the best nucleobase binding sites for divalent metals. Further, Mg2+ coordination to N7 has been implied in several ribo...

Ca2+-ATPase activity has been characterized in Streptomyces griseus. The enzyme has a pH optimum of 8.5 at 37 degrees C. Its Ca2+ requirement can be substituted by Cd2+, Zn2+ and Mn2+. Mg2+ inhibits the enzyme non-competitively.

The use of dead, dried aquatic plants, for water removal of metals derived from industrial activities as a simple biosorbent material has been increasing in the last years. The mechanism of simultaneous metal removal (Cd2+, Ni2+, Cu2+, Zn2+ and Pb2+) by 3 macrophytes biomass (Spirodela intermedia, Lemna minor and Pistia stratiotes) was investigated. L. minor biomass presented the highest mean r...

Extracellular polymeric substances (EPSs) were extracted by high-speed centrifugation at 20,000 G for 30 min from an activated sludge treating municipal wastewater. Each gram of sludge, as measured in volatile suspended solids (VSS), contained 7.3 mg of EPS, including 6.5 mg of protein (EPSp) and 0.8 mg of carbohydrate (EPSc). The EPSp had a mean MW of 2.0 x 105; about 18% of EPSp had MW over 5...