Objective: Thalassemic patients are at risk of zinc deficiency due to various causes including desferal injection, hyperzincuria, high ferritin levels, and hepatic iron overload. We evaluate the effect of zinc supplementation on linear growth of beta-thalassemia patients. Methods: one-hundred beta-thalassemic major patients whose heights were within 3rd to l0th percentile were randomly divided ...

BACKGROUND Gestational zinc deficiency has been confirmed to impair the infant immune function. However, knowledge about effects of maternal mild zinc deficiency during pregnancy on hepatitis B vaccine responsiveness in offspring is limited. In this report, we aimed to examine how maternal zinc deficiency during pregnancy influences humoral and cellular immune responses to hepatitis B vaccinati...

OBJECTIVE Major depression is a mood disorder that causes changes in physical activity, appetite, sleep and weight. Regarding the role of zinc in the pathology of depression, the present study was aimed to investigate the effects of zinc supplementation in the treatment of this disease. METHODS This study was a double-blind randomized clinical trial. Forty four patients with major depression ...

We are in the midst of an epidemic of Alzheimer's disease (AD) in developed countries. We have postulated that ingestion of inorganic copper from drinking water and taking supplement pills and a high fat diet are major causative factors. Ingestion of inorganic copper can directly raise the blood free copper level. Blood free copper has been shown by the Squitti group to be elevated in AD, to co...

Trace element deficiencies commonly encountered in Japanese infants and children are discussed. Premature birth infants have a high likelihood of developing deficiency of trace elements such as iron, zinc, and selenium, during the period of rapid growth from 2 months to 6 months of age. Breast-fed infants, in particular, are prone to develop trace element deficiency, and alopecia and dermatitis...

zinc (zn) is an essential trace element in all living organisms, and the first eukaryotic zn uptake transporter was discovered in the yeast, saccharomyces cerevisiae. zinc-enriched yeast is a currently available zn supplement. the purpose of the investigation was to compare and evaluate the effect of zn enriched yeast in rainbow trout. the fish (mean body weight 10 ± 0.5 g) were fed a commercia...

OBJECTIVE The aims of the present study were to examine the Zn intake and characteristics of Zn supplement users and non-users and to survey Zn supplements that are commercially available. DESIGN Cross-sectional national nutrition survey (2007 Australian Children's Nutrition and Physical Activity Survey) and a review of commercially available Zn supplements. SETTING Australia. SUBJECTS Ch...

OBJECTIVE In a zinc supplementation trial (with a significant impact on diarrheal morbidity), to evaluate effect of zinc supplementation on cellular immune status before and after 120 days of supplementation. DESIGN A double blind, randomized controlled trial with immune assessment at baseline and after 120 days on supplement. SETTING Community based study in an urban slum population. SUB...