objective: endothelial progenitor cells (epcs) have a potential application for cell therapy, however, their biological nature is not well-understood. epcs also possess some stemness features, such as their clonogenicity and differentiation capacity. the main aim of this study was to evaluate the expression of certain transcription factors regulating self-renewal property of stem cells. materia...

The Sleeping Beauty (SB) transposon mutagenesis system is a powerful tool that facilitates the discovery of mutations that accelerate tumorigenesis. In this study, we sought to identify mutations that cooperate with MYC, one of the most commonly dysregulated genes in human malignancy. We performed a forward genetic screen with a mouse model of MYC-induced liver cancer using SB-mediated mutagene...