Adolescents and young adults (AYAs) have lower rates of clinical trial enrollment than younger or older patients with cancer. Multiple approaches to change policy and practice need to be used to improve this statistic. This article examines the option of increasing referral to 3 types of centers that are known to have relatively higher rates of enrollment of AYAs: pediatric cancer centers, AYA ...

BACKGROUND Intergenerational effects of child abuse have been documented, but it is unknown whether maternal childhood abuse influences offspring mental health in adolescence or adulthood. METHODS To examine whether maternal experience of childhood abuse is associated with depressive symptoms in adolescent and young adult offspring, we linked data from two large longitudinal cohorts of women ...

Limited information exists on how adolescents decide to use complementary/alternative medicine (CAM). There are also no instruments specific to CAM, for the young adult population, which makes it difficult to explore knowledge in this area. The purpose of this study was to develop and examine the psychometric properties of the CAM Questionnaire for Young Adults which measures young adults' atti...

Despite overall improvement in survival, morbidity, and quality of life of US patients with cancer, this progress is less prevalent in the population of adolescent and young adult patients with cancer, including those between the ages of 15 and 19 years. Evidence suggests that participation in clinical trials is associated with better survival outcomes among children and adolescents with cancer...

The purpose of the present study was to use a previously developed treadmill walking test to determine training-induced changes within and between two groups of untrained men during a six week training period. One group consisted of seven middle-aged (mean age, 41.3 yr), and the second group consisted of seven young adult (mean age, 19.9 yr), men. Heart rates following training were significant...

Individuals born small for gestational age (SGA) are supposed to be at higher risk to develop cardiovascular disorders, and recent report showed that concurrent obesity influences blood pressure (BP) in SGA children. Our aim was to investigate the impact of obesity and birth weight on blood pressure values in young adult men born SGA and controls born after normal pregnancy, Normotensive, non-t...

One of the main components of the stress system is hypothalamus- pituitary-adrenal (HPA) axis. Acute activation of µ-opioid receptors increases the activity of the HPA axis, leading to release of ACTH and corticosterone. Glucocorticoids can change behaviors, depend on age but there were no evidences about the interaction between age, opioid system and glucocorticoids. In this experiment, ...

OBJECTIVE Alcohol-impaired driving persists as a major cause of traffic fatalities and injuries among young drivers. This meta-analysis examined whether brief alcohol interventions were effective in reducing driving after drinking among adolescents and young adults. METHOD Our systematic search identified 12 experimental/quasi-experimental evaluations (16 intervention groups) that measured dr...

This final report describes the results of the research conducted in the project «Development of improved methods or basis for medical age assessments of minors and young adults». The aim of the project has been to contribute to develop improved methods for measuring physical developments of a child or young adult and for assessing the chronological age based on such measurements, giving an imp...

Inflammatory bowel disease (IBD) is a heterogeneous group of chronic diseases with a rising prevalence in the pediatric population, and up to 25% of IBD patients are diagnosed before 18 years of age. Adolescents with IBD tend to have more severe and extensive disease and eventually require graduation from pediatric care toadult services. The transition of patients from pediatric to adult gastro...