Populations of bank voles (Clethrionomys glareolus) were monitored during a 4-year study in southern Belgium to assess the influence of agonistic behavior, reproductive status, mobility, and distribution of the rodents on the dynamics of Puumala virus (abbreviation: PUUV; genus: Hantavirus) infection. Concordance was high between data from serologic testing and results of viral RNA detection. W...

A period of aggressive surgical treatment of early identification of fungal infection of the burn wound was compared with the previous 5 years' experience with patients suffering from fungal infection of burn wounds. The portion of those patients with Candida infections diagnosed and treated premortem increased from 48.0% to 63.6% and of patients with noncandidal infections from 40.8% to 67.0% ...

Intact human skin surface is essential for protection against infection, preservation of body fluid homeostasis and thermoregulation. Burn injury compromises the skin barrier and enables bacterial infection, hence delaying burn wound healing. This study aimed to determine the microbial profile of burn wounds, and resistance patterns of microbes with respect to the source of the injured patient'...

OBJECTIVE To assess the results of single-stage treatment of infected sternotomy wounds using bilateral pectorals major myocutaneous advancement flaps. METHODS Between January 2000 and July 2007, 1972 heart surgeries with median transesternal thoracotomy were performed. Thirteen (0.65%) patients presented wound infections and dehiscence after sternotomy. To treat those patients we adopted exc...

Normal wound healing in adults follows an ordered progression of events, which ultimately results in wound closure. In some cases, however, wound closure may not occur. There are many reasons why a wound will fail to heal, including both local (e.g. the presence of a foreign body or infection) and systemic (e.g. malnutrition or diabetes) factors. In a slow-healing or non-healing wound, it is im...

Background:Honey has been shown to accelerate wound healing, which is especially important in the management of patients with full-thickness wounds of skin in dermatologic surgeries. Objective: To evaluate the effects of honey in accelerating healing of full-thickness skin wounds in mice. Methods: Two groups of male NMRI mice (n=12) were subjected to full-thickness skin wounds under general ane...

Despite many advances in surgery, wound infection continues to be a common problem (1,2,3). It increases the morbidity and cost of patient care (4). Many hospitals have wound care teams and regular surveillance of wounds (5). A prospective study was carried out from July to December 1997. A senior staff nurse was assigned to col­ lect data from patient records before and after surgery. The grad...

Diabetic foot ulcers are responsible for more hospitalizations than any other complication of diabetes. Bacterial infection is recognized as an important factor associated with impaired healing in diabetic ulcers. Pseudomonas aeruginosa is the most frequently detected Gram-negative pathogen in diabetic ulcers. P. aeruginosa infection has been shown to impair healing in diabetic wounds in a mann...

Advanced wound management of complex surgical wounds remains a significant challenge as more patients are being hospitalized with infected wounds. Reducing recurrent infections and promoting granulation tissue formation is essential to overall wound healing. Wounds with acute infection and critical colonization require advanced multimodal approaches including systemic antibiotics, surgical debr...

Wounds may fail to heal because tension, infection, hematoma or seroma formation, ischemia, molestation, pressure, motion, foreign materials, neoplasia, drugs (corticosteroids, neoplasia), radiation, severe malnutrition, or underlying metabolic disease. When wounds fail to heal, the veterinarian should examine and treat the animal for underlying disease, culture a punch biopsy of the wound to e...